{"slug":"bio-basecalling","source_name":"bio-basecalling","name":"Bio Basecalling","description":"Convert raw Nanopore signal data (FAST5/POD5) to nucleotide sequences using Dorado basecaller. Covers model selection, GPU acceleration, modified base detection, and quality filtering. Use when processing raw Nanopore data before alignment. Guppy is deprecated; use Dorado for all new analyses.","version":1,"lift":{"pass_rate_delta_pts":22.73,"pass_rate_pct":36.4,"total_cases":22,"passed_cases":8,"tokens_delta_pct":90.2,"turns_delta_pct":0,"verdict":"mixed","benchmark_model":"gemini-3.6-flash","grading_method":"judged","completed_at":"2026-07-26T06:47:45.938102+00:00"},"skill_score":0.3636,"benchmark_models":[{"model":"gemini-3.6-flash","headline":true,"delta_pts":22.73,"with_pass_pct":36.4,"without_pass_pct":13.6,"tokens_delta_pct":90.2,"turns_delta_pct":0,"total_cases":22,"cases_aggregated":22,"verdict":"mixed","never_hurt":true,"completed_at":"2026-07-26T06:47:45.938102+00:00","run_id":"2c39a5fe-ed54-4681-92c7-b63f19377a74","version_number":1,"is_latest_version":true,"gate":null}],"trust":{"skill_safety":"passed","safety_status":"clean","intent_verdict":null,"content_status":"clean","indexable":true},"license":null,"install_count":0,"manifest_hash":"5217c7e305b488eb59c17fb809d24f08d02b0066caba36b0304e742602bdaf42","raw_url":"https://app.decimal.ai/s/bio-basecalling/SKILL.md","scorecard_url":"https://app.decimal.ai/skills/bio-basecalling"}