{"slug":"bio-cfdna-preprocessing","source_name":"bio-cfdna-preprocessing","name":"Bio Cfdna Preprocessing","description":"Preprocesses cell-free DNA sequencing data including adapter trimming, alignment optimized for short fragments, and UMI-aware duplicate removal using fgbio. Applies cfDNA-specific quality thresholds and fragment length filtering. Use when processing plasma cfDNA sequencing data before downstream analysis.","version":1,"lift":{"pass_rate_delta_pts":31.82,"pass_rate_pct":63.6,"total_cases":22,"passed_cases":14,"tokens_delta_pct":46.8,"turns_delta_pct":0,"verdict":"mixed","benchmark_model":"gemini-3.6-flash","grading_method":"judged","completed_at":"2026-07-24T07:29:57.082403+00:00"},"skill_score":0.6364,"benchmark_models":[{"model":"gemini-3.6-flash","headline":true,"delta_pts":31.82,"with_pass_pct":63.6,"without_pass_pct":31.8,"tokens_delta_pct":46.8,"turns_delta_pct":0,"total_cases":22,"cases_aggregated":22,"verdict":"mixed","never_hurt":false,"completed_at":"2026-07-24T07:29:57.082403+00:00","run_id":"e6a01a7a-0feb-4521-8947-a62d54a9c705","version_number":1,"is_latest_version":true,"gate":null}],"trust":{"skill_safety":"passed","safety_status":"clean","intent_verdict":null,"content_status":"clean","indexable":true},"license":null,"install_count":0,"manifest_hash":"60fa3824feabd083fcd11373718ff2048df98122bf6692848bcaa2c82b443763","raw_url":"https://app.decimal.ai/s/bio-cfdna-preprocessing/SKILL.md","scorecard_url":"https://app.decimal.ai/skills/bio-cfdna-preprocessing"}