{"slug":"clawbio-wgs-prs","source_name":"clawbio/wgs-prs","name":"Clawbio/Wgs Prs","description":"End-to-end WGS to polygenic risk score pipeline. Takes paired-end FASTQ files (or a pre-existing VCF) through nf-core/sarek for variant calling, applies VCF QC (normalisation, hard filtering, Ti/Tv and Het/Hom checks), then computes polygenic risk scores via the PGS Catalog. Fills the FASTQ to VCF gap upstream of the gwas-prs skill.","version":1,"lift":{"pass_rate_delta_pts":72.73,"pass_rate_pct":100,"total_cases":22,"passed_cases":22,"tokens_delta_pct":55.8,"turns_delta_pct":0,"verdict":"pass","benchmark_model":"gemini-3.6-flash","grading_method":"judged","completed_at":"2026-08-16T10:23:01.067617+00:00"},"skill_score":1,"benchmark_models":[{"model":"gemini-3.6-flash","headline":true,"delta_pts":72.73,"with_pass_pct":100,"without_pass_pct":27.3,"tokens_delta_pct":55.8,"turns_delta_pct":0,"total_cases":22,"cases_aggregated":22,"verdict":"pass","never_hurt":true,"completed_at":"2026-08-16T10:23:01.067617+00:00","run_id":"e4da62b8-f312-4b80-a886-c6b8bfd9dad5","version_number":1,"is_latest_version":true,"gate":null}],"trust":{"skill_safety":"passed","safety_status":"clean","intent_verdict":"safe","content_status":"clean","indexable":true},"license":"MIT","install_count":0,"manifest_hash":"4852861c34f10d3a5f98e33ba4b194e76f5701506be95a1d35b9a62aa07d5adf","raw_url":"https://app.decimal.ai/s/clawbio-wgs-prs/SKILL.md","scorecard_url":"https://app.decimal.ai/skills/clawbio-wgs-prs"}