{"slug":"jaechang-hits-snpeff-variant-annotation","source_name":"jaechang-hits/snpeff-variant-annotation","name":"Jaechang Hits/Snpeff Variant Annotation","description":"Annotate and filter VCF variants with SnpEff and SnpSift. SnpEff predicts functional effects (HIGH/MODERATE/LOW/MODIFIER), genes, transcripts, AA changes, HGVS; SnpSift filters and adds ClinVar/dbSNP. Java CLI with Python subprocess integration. Use ANNOVAR for multi-database annotation; Ensembl VEP for REST API; SnpEff for fast CLI with pre-built genomes.","version":1,"lift":{"pass_rate_delta_pts":27.27,"pass_rate_pct":100,"total_cases":22,"passed_cases":22,"tokens_delta_pct":317.6,"turns_delta_pct":0,"verdict":"pass","benchmark_model":"gemini-3.6-flash","grading_method":"judged","completed_at":"2026-08-24T12:02:44.155442+00:00"},"skill_score":1,"benchmark_models":[{"model":"gemini-3.6-flash","headline":true,"delta_pts":27.27,"with_pass_pct":100,"without_pass_pct":72.7,"tokens_delta_pct":317.6,"turns_delta_pct":0,"total_cases":22,"cases_aggregated":21,"verdict":"pass","never_hurt":true,"completed_at":"2026-08-24T12:02:44.155442+00:00","run_id":"74f87370-c17e-47df-8890-f94821578be6","version_number":1,"is_latest_version":true,"gate":null}],"trust":{"skill_safety":"passed","safety_status":"clean","intent_verdict":"safe","content_status":"clean","indexable":true},"license":"MIT","install_count":0,"manifest_hash":"ff974a8d75bc64a4630877f3bf135f1b9853e4a9bb3d1aff5271cde2760c9e00","raw_url":"https://app.decimal.ai/s/jaechang-hits-snpeff-variant-annotation/SKILL.md","scorecard_url":"https://app.decimal.ai/skills/jaechang-hits-snpeff-variant-annotation"}