{"slug":"mims-harvard-tooluniverse-cancer-variant-interpretation","source_name":"mims-harvard/tooluniverse-cancer-variant-interpretation","name":"Mims Harvard/Tooluniverse Cancer Variant Interpretation","description":"Clinical interpretation of somatic cancer mutations for precision oncology. Transforms a gene + variant + cancer-type input into an actionable report: clinical evidence tier (CIViC, OncoKB), therapeutic options (FDA-approved + investigational), resistance mechanisms, prognosis, and matching clinical trials. Use for tumor-board variant calls, somatic-mutation actionability assessment, and treatment selection. Always cancer-type-specific.","version":1,"lift":{"pass_rate_delta_pts":27.27,"pass_rate_pct":63.6,"total_cases":22,"passed_cases":14,"tokens_delta_pct":156.2,"turns_delta_pct":0,"verdict":"mixed","benchmark_model":"gemini-3.6-flash","grading_method":"judged","completed_at":"2026-08-06T14:30:39.392670+00:00"},"skill_score":0.6364,"benchmark_models":[{"model":"gemini-3.6-flash","headline":true,"delta_pts":27.27,"with_pass_pct":63.6,"without_pass_pct":36.4,"tokens_delta_pct":156.2,"turns_delta_pct":0,"total_cases":22,"cases_aggregated":15,"verdict":"mixed","never_hurt":false,"completed_at":"2026-08-06T14:30:39.392670+00:00","run_id":"0f5e9f70-c44c-4943-b13e-5e6fc9f7d659","version_number":1,"is_latest_version":true,"gate":null}],"trust":{"skill_safety":"passed","safety_status":"clean","intent_verdict":"safe","content_status":"clean","indexable":true},"license":"Apache-2.0","install_count":0,"manifest_hash":"9cd9103fa71a908e536e88f1608b84b5cdfc175e58f1b19c9dd86339414bf6c4","raw_url":"https://app.decimal.ai/s/mims-harvard-tooluniverse-cancer-variant-interpretation/SKILL.md","scorecard_url":"https://app.decimal.ai/skills/mims-harvard-tooluniverse-cancer-variant-interpretation"}