{"slug":"mims-harvard-tooluniverse-clinical-trial-design","source_name":"mims-harvard/tooluniverse-clinical-trial-design","name":"Mims Harvard/Tooluniverse Clinical Trial Design","description":"Strategic clinical trial design feasibility assessment. Analyzes 6 dimensions (endpoint, population, comparator, effect size, duration, regulatory pathway) using precedent trials and FDA guidance. Produces enrollment projections, endpoint recommendations, and approval-pathway analysis. Use for trial-protocol design, power/sample-size estimation, comparator selection, and FDA submission strategy. Driven by precedent-based reasoning rather than first-principles math.","version":1,"lift":{"pass_rate_delta_pts":4.55,"pass_rate_pct":54.5,"total_cases":22,"passed_cases":12,"tokens_delta_pct":134.5,"turns_delta_pct":0,"verdict":"mixed","benchmark_model":"gemini-3.6-flash","grading_method":"judged","completed_at":"2026-08-06T14:50:18.058101+00:00"},"skill_score":0.5455,"benchmark_models":[{"model":"gemini-3.6-flash","headline":true,"delta_pts":4.55,"with_pass_pct":54.5,"without_pass_pct":50,"tokens_delta_pct":134.5,"turns_delta_pct":0,"total_cases":22,"cases_aggregated":14,"verdict":"mixed","never_hurt":false,"completed_at":"2026-08-06T14:50:18.058101+00:00","run_id":"63b50387-d9b9-4d58-94ed-24ced27adc1c","version_number":1,"is_latest_version":true,"gate":null}],"trust":{"skill_safety":"passed","safety_status":"clean","intent_verdict":"safe","content_status":"clean","indexable":true},"license":"Apache-2.0","install_count":0,"manifest_hash":"b27c57caef09f825ed19b385e07b1c0fab205568bd5d45fdfa21c30b34bc1c72","raw_url":"https://app.decimal.ai/s/mims-harvard-tooluniverse-clinical-trial-design/SKILL.md","scorecard_url":"https://app.decimal.ai/skills/mims-harvard-tooluniverse-clinical-trial-design"}