{"slug":"mims-harvard-tooluniverse-drug-synergy","source_name":"mims-harvard/tooluniverse-drug-synergy","name":"Mims Harvard/Tooluniverse Drug Synergy","description":"Drug-combination synergy analysis — quantify whether two drugs together are synergistic, additive, or antagonistic using the standard reference models (Bliss independence, HSA / highest single agent, Loewe additivity, ZIP, and the Chou-Talalay Combination Index). Use when you have measured single-drug and combination effects (inhibition/viability) and need a synergy score. Explains which model to use, what data each one needs, and how to read the score. NOT for looking up pre-computed synergy in","version":1,"lift":{"pass_rate_delta_pts":13.64,"pass_rate_pct":90.9,"total_cases":22,"passed_cases":20,"tokens_delta_pct":41.4,"turns_delta_pct":0,"verdict":"mixed","benchmark_model":"gemini-3.6-flash","grading_method":"judged","completed_at":"2026-08-06T15:40:50.200843+00:00"},"skill_score":0.9091,"benchmark_models":[{"model":"gemini-3.6-flash","headline":true,"delta_pts":13.64,"with_pass_pct":90.9,"without_pass_pct":77.3,"tokens_delta_pct":41.4,"turns_delta_pct":0,"total_cases":22,"cases_aggregated":19,"verdict":"mixed","never_hurt":false,"completed_at":"2026-08-06T15:40:50.200843+00:00","run_id":"05a44c19-a324-4869-93b8-32a549666974","version_number":1,"is_latest_version":true,"gate":null}],"trust":{"skill_safety":"passed","safety_status":"clean","intent_verdict":"safe","content_status":"clean","indexable":true},"license":"Apache-2.0","install_count":0,"manifest_hash":"dd011070f7d8e6085489e7a6d266765e910040b3a13d02f41c67384cb8d5cc43","raw_url":"https://app.decimal.ai/s/mims-harvard-tooluniverse-drug-synergy/SKILL.md","scorecard_url":"https://app.decimal.ai/skills/mims-harvard-tooluniverse-drug-synergy"}