{"slug":"mims-harvard-tooluniverse-immunotherapy-response-prediction","source_name":"mims-harvard/tooluniverse-immunotherapy-response-prediction","name":"Mims Harvard/Tooluniverse Immunotherapy Response Prediction","description":"Predict patient response to immune checkpoint inhibitors (ICIs) by integrating tumor mutational burden (TMB), microsatellite instability (MSI), PD-L1 expression, HLA status, and immune-related gene expression. Outputs ICI Response Score with drug-specific recommendations and resistance-risk assessment. Use for melanoma/NSCLC/RCC immunotherapy decision support.","version":1,"lift":{"pass_rate_delta_pts":null,"pass_rate_pct":18.2,"total_cases":22,"passed_cases":4,"tokens_delta_pct":146,"turns_delta_pct":0,"verdict":"mixed","benchmark_model":"gemini-3.6-flash","grading_method":"judged","completed_at":"2026-08-08T16:05:34.782827+00:00"},"skill_score":null,"benchmark_models":[{"model":"gemini-3.6-flash","headline":false,"delta_pts":null,"with_pass_pct":null,"without_pass_pct":null,"tokens_delta_pct":146,"turns_delta_pct":0,"total_cases":22,"cases_aggregated":4,"verdict":"mixed","never_hurt":false,"completed_at":"2026-08-08T16:05:34.782827+00:00","run_id":"81983396-5528-481b-92dd-1de64a11d8fa","version_number":1,"is_latest_version":true,"gate":"underpowered"}],"trust":{"skill_safety":"passed","safety_status":"clean","intent_verdict":"safe","content_status":"clean","indexable":true},"license":"Apache-2.0","install_count":0,"manifest_hash":"d512587e7c84f1a2d7f3f34b74a1e6c598bd62b0623330889a9281834dbb3915","raw_url":"https://app.decimal.ai/s/mims-harvard-tooluniverse-immunotherapy-response-prediction/SKILL.md","scorecard_url":"https://app.decimal.ai/skills/mims-harvard-tooluniverse-immunotherapy-response-prediction"}