{"slug":"mims-harvard-tooluniverse-pathway-disease-genetics","source_name":"mims-harvard/tooluniverse-pathway-disease-genetics","name":"Mims Harvard/Tooluniverse Pathway Disease Genetics","description":"Connect GWAS variants to biological pathways and druggable targets. Maps GWAS hits to causal genes (via fine-mapping/eQTL), then to pathways (Reactome, KEGG, WikiPathways), then to existing drugs hitting those pathways. Use for pathway-level disease mechanisms, druggable-pathway prioritization from GWAS, SNP-to-pathway-to-target tracing, and tissue-specific eQTL evidence for drug target hypotheses.","version":1,"lift":{"pass_rate_delta_pts":8.7,"pass_rate_pct":39.1,"total_cases":23,"passed_cases":9,"tokens_delta_pct":154.8,"turns_delta_pct":0,"verdict":"mixed","benchmark_model":"gemini-3.6-flash","grading_method":"judged","completed_at":"2026-08-06T16:11:57.258265+00:00"},"skill_score":0.3913,"benchmark_models":[{"model":"gemini-3.6-flash","headline":true,"delta_pts":8.7,"with_pass_pct":39.1,"without_pass_pct":30.4,"tokens_delta_pct":154.8,"turns_delta_pct":0,"total_cases":23,"cases_aggregated":10,"verdict":"mixed","never_hurt":false,"completed_at":"2026-08-06T16:11:57.258265+00:00","run_id":"006e173c-04e7-4c81-8a78-d2b28be3665c","version_number":1,"is_latest_version":true,"gate":null}],"trust":{"skill_safety":"passed","safety_status":"clean","intent_verdict":"safe","content_status":"clean","indexable":true},"license":"Apache-2.0","install_count":0,"manifest_hash":"a63211f71d62f2baff310b9fe42d8de80f2f7c6bec3152f5b96e1bf92044046b","raw_url":"https://app.decimal.ai/s/mims-harvard-tooluniverse-pathway-disease-genetics/SKILL.md","scorecard_url":"https://app.decimal.ai/skills/mims-harvard-tooluniverse-pathway-disease-genetics"}