{"slug":"mims-harvard-tooluniverse-peptide-target-deorphanization","source_name":"mims-harvard/tooluniverse-peptide-target-deorphanization","name":"Mims Harvard/Tooluniverse Peptide Target Deorphanization","description":"Find the real protein target(s) of a peptide from its sequence — peptide target deorphanization / off-target identification, for ANY target class (GPCR, ion channel, protease, cytokine/growth-factor receptor, enzyme, integrin), not only GPCRs. Use when a peptide has a phenotype but does not bind its hypothesized target, when a peptide binds a target in one species or assay but not another, or to screen candidate targets for an orphan peptide. A target-class router steers a multi-route keyless pi","version":1,"lift":{"pass_rate_delta_pts":36.36,"pass_rate_pct":68.2,"total_cases":22,"passed_cases":15,"tokens_delta_pct":124.1,"turns_delta_pct":0,"verdict":"mixed","benchmark_model":"gemini-3.6-flash","grading_method":"judged","completed_at":"2026-08-06T16:24:02.872175+00:00"},"skill_score":0.6818,"benchmark_models":[{"model":"gemini-3.6-flash","headline":true,"delta_pts":36.36,"with_pass_pct":68.2,"without_pass_pct":31.8,"tokens_delta_pct":124.1,"turns_delta_pct":0,"total_cases":22,"cases_aggregated":20,"verdict":"mixed","never_hurt":false,"completed_at":"2026-08-06T16:24:02.872175+00:00","run_id":"cccd1c09-ca13-442c-b1b4-999d7ebf9c4f","version_number":1,"is_latest_version":true,"gate":null}],"trust":{"skill_safety":"passed","safety_status":"clean","intent_verdict":"safe","content_status":"clean","indexable":true},"license":"Apache-2.0","install_count":0,"manifest_hash":"61fee92ff07604a77f6d3c115547f7579a42756ea04722035666dc6890b59fc4","raw_url":"https://app.decimal.ai/s/mims-harvard-tooluniverse-peptide-target-deorphanization/SKILL.md","scorecard_url":"https://app.decimal.ai/skills/mims-harvard-tooluniverse-peptide-target-deorphanization"}