{"slug":"tooluniverse-mendelian-randomization","source_name":"tooluniverse-mendelian-randomization","name":"Tooluniverse Mendelian Randomization","description":"Mendelian randomization (MR) causal inference — does an exposure, risk factor, or biomarker CAUSALLY affect a disease/outcome, using genetic variants as instrumental variables (IEU OpenGWAS / EpiGraphDB MR-EvE). Use this whenever the user asks if X causes Y, whether an observational association is actually causal or just correlation, if a biomarker/trait is a causal risk factor, wants to triangulate epidemiology against genetic evidence, or mentions Mendelian randomization, instrumental-variable","version":1,"lift":{"pass_rate_delta_pts":27.27,"pass_rate_pct":31.8,"total_cases":22,"passed_cases":7,"tokens_delta_pct":98.2,"turns_delta_pct":0,"verdict":"mixed","benchmark_model":"gemini-3.6-flash","grading_method":"judged","completed_at":"2026-07-27T22:15:41.749089+00:00"},"skill_score":0.3182,"benchmark_models":[{"model":"gemini-3.6-flash","headline":true,"delta_pts":27.27,"with_pass_pct":31.8,"without_pass_pct":4.5,"tokens_delta_pct":98.2,"turns_delta_pct":0,"total_cases":22,"cases_aggregated":17,"verdict":"mixed","never_hurt":false,"completed_at":"2026-07-27T22:15:41.749089+00:00","run_id":"1b906a0e-bb37-40cb-b10a-d4180a6f793a","version_number":1,"is_latest_version":true,"gate":null}],"trust":{"skill_safety":"passed","safety_status":"clean","intent_verdict":"safe","content_status":"clean","indexable":true},"license":"Apache-2.0","install_count":0,"manifest_hash":"2310f35ffba1630263792e80cab08289fa7ffcf17cdc32f07094092c218368e9","raw_url":"https://app.decimal.ai/s/tooluniverse-mendelian-randomization/SKILL.md","scorecard_url":"https://app.decimal.ai/skills/tooluniverse-mendelian-randomization"}