{"slug":"tooluniverse-pathway-disease-genetics","source_name":"tooluniverse-pathway-disease-genetics","name":"Tooluniverse Pathway Disease Genetics","description":"Connect GWAS variants to biological pathways and druggable targets. Maps GWAS hits to causal genes (via fine-mapping/eQTL), then to pathways (Reactome, KEGG, WikiPathways), then to existing drugs hitting those pathways. Use for pathway-level disease mechanisms, druggable-pathway prioritization from GWAS, SNP-to-pathway-to-target tracing, and tissue-specific eQTL evidence for drug target hypotheses.","version":1,"lift":{"pass_rate_delta_pts":21.74,"pass_rate_pct":21.7,"total_cases":23,"passed_cases":5,"tokens_delta_pct":131.1,"turns_delta_pct":0,"verdict":"mixed","benchmark_model":"gemini-3.6-flash","grading_method":"judged","completed_at":"2026-07-27T22:23:42.148304+00:00"},"skill_score":0.2174,"benchmark_models":[{"model":"gemini-3.6-flash","headline":true,"delta_pts":21.74,"with_pass_pct":21.7,"without_pass_pct":0,"tokens_delta_pct":131.1,"turns_delta_pct":0,"total_cases":23,"cases_aggregated":15,"verdict":"mixed","never_hurt":false,"completed_at":"2026-07-27T22:23:42.148304+00:00","run_id":"fb4e7928-d94b-444b-b2d1-93de35bbaec2","version_number":1,"is_latest_version":true,"gate":null}],"trust":{"skill_safety":"passed","safety_status":"clean","intent_verdict":null,"content_status":"clean","indexable":true},"license":"Apache-2.0","install_count":0,"manifest_hash":"a63211f71d62f2baff310b9fe42d8de80f2f7c6bec3152f5b96e1bf92044046b","raw_url":"https://app.decimal.ai/s/tooluniverse-pathway-disease-genetics/SKILL.md","scorecard_url":"https://app.decimal.ai/skills/tooluniverse-pathway-disease-genetics"}