{"slug":"tooluniverse-protein-therapeutic-design","source_name":"tooluniverse-protein-therapeutic-design","name":"Tooluniverse Protein Therapeutic Design","description":"Design novel protein therapeutics (binders, enzymes, scaffolds) using AI-guided de novo design. Uses RFdiffusion for backbone generation, ProteinMPNN for sequence design, ESMFold/AlphaFold2 for validation. Use when asked to design protein binders, therapeutic proteins, or engineer protein function.","version":1,"lift":{"pass_rate_delta_pts":40,"pass_rate_pct":44,"total_cases":25,"passed_cases":11,"tokens_delta_pct":248.9,"turns_delta_pct":0,"verdict":"mixed","benchmark_model":"gemini-3.6-flash","grading_method":"judged","completed_at":"2026-07-26T13:59:00.714354+00:00"},"skill_score":0.44,"benchmark_models":[{"model":"gemini-3.6-flash","headline":true,"delta_pts":40,"with_pass_pct":44,"without_pass_pct":4,"tokens_delta_pct":248.9,"turns_delta_pct":0,"total_cases":25,"cases_aggregated":21,"verdict":"mixed","never_hurt":false,"completed_at":"2026-07-26T13:59:00.714354+00:00","run_id":"d9794bc7-5f71-4142-91e8-84925a990353","version_number":1,"is_latest_version":true,"gate":null}],"trust":{"skill_safety":"passed","safety_status":"clean","intent_verdict":null,"content_status":"clean","indexable":true},"license":null,"install_count":0,"manifest_hash":"f3d562cbb38e798e29642afec56e3f89fd46742ba58e7d0bdddb4c2d0c7de68e","raw_url":"https://app.decimal.ai/s/tooluniverse-protein-therapeutic-design/SKILL.md","scorecard_url":"https://app.decimal.ai/skills/tooluniverse-protein-therapeutic-design"}