{"slug":"tooluniverse-structural-variant-analysis","source_name":"tooluniverse-structural-variant-analysis","name":"Tooluniverse Structural Variant Analysis","description":"Comprehensive structural variant (SV) analysis skill for clinical genomics. Classifies SVs (deletions, duplications, inversions, translocations), assesses pathogenicity using ACMG-adapted criteria, evaluates gene disruption and dosage sensitivity, and provides clinical interpretation with evidence grading. Use when analyzing CNVs, large deletions/duplications, chromosomal rearrangements, or any structural variants requiring clinical interpretation.","version":1,"lift":{"pass_rate_delta_pts":18.18,"pass_rate_pct":22.7,"total_cases":22,"passed_cases":5,"tokens_delta_pct":571.8,"turns_delta_pct":0,"verdict":"mixed","benchmark_model":"gemini-3.6-flash","grading_method":"judged","completed_at":"2026-07-27T06:51:51.534450+00:00"},"skill_score":0.2273,"benchmark_models":[{"model":"gemini-3.6-flash","headline":true,"delta_pts":18.18,"with_pass_pct":22.7,"without_pass_pct":4.5,"tokens_delta_pct":571.8,"turns_delta_pct":0,"total_cases":22,"cases_aggregated":13,"verdict":"mixed","never_hurt":false,"completed_at":"2026-07-27T06:51:51.534450+00:00","run_id":"c98168ce-41d1-4312-9e4e-355f46afd144","version_number":1,"is_latest_version":true,"gate":null}],"trust":{"skill_safety":"passed","safety_status":"clean","intent_verdict":null,"content_status":"clean","indexable":true},"license":null,"install_count":0,"manifest_hash":"08191d4be43686d089776487f3bd02f42ba22f35072f5eeeaab53a122b31690f","raw_url":"https://app.decimal.ai/s/tooluniverse-structural-variant-analysis/SKILL.md","scorecard_url":"https://app.decimal.ai/skills/tooluniverse-structural-variant-analysis"}