{"slug":"tooluniverse-variant-to-mechanism","source_name":"tooluniverse-variant-to-mechanism","name":"Tooluniverse Variant To Mechanism","description":"End-to-end variant-to-mechanism analysis — trace a variant (rsID/coordinates) through regulatory context, target gene(s), molecular pathway(s), and phenotypic consequences. Integrates 7+ databases across 3 evidence layers (regulatory, molecular, disease) for a mechanistic model. Use for GWAS-hit-to-mechanism, eQTL-causal-gene tracing, and full causal-chain reports.","version":1,"lift":{"pass_rate_delta_pts":39.13,"pass_rate_pct":43.5,"total_cases":23,"passed_cases":10,"tokens_delta_pct":234.3,"turns_delta_pct":0,"verdict":"mixed","benchmark_model":"gemini-3.6-flash","grading_method":"judged","completed_at":"2026-07-27T23:28:17.574620+00:00"},"skill_score":0.4348,"benchmark_models":[{"model":"gemini-3.6-flash","headline":true,"delta_pts":39.13,"with_pass_pct":43.5,"without_pass_pct":4.3,"tokens_delta_pct":234.3,"turns_delta_pct":0,"total_cases":23,"cases_aggregated":16,"verdict":"mixed","never_hurt":false,"completed_at":"2026-07-27T23:28:17.574620+00:00","run_id":"037a9d23-82ed-4b10-818a-4b60b0a234e6","version_number":1,"is_latest_version":true,"gate":null}],"trust":{"skill_safety":"passed","safety_status":"clean","intent_verdict":null,"content_status":"clean","indexable":true},"license":"Apache-2.0","install_count":0,"manifest_hash":"d7279d4445815b94cfb199761ca2ce84feae98bfa13e6cbd0fd20514e0242805","raw_url":"https://app.decimal.ai/s/tooluniverse-variant-to-mechanism/SKILL.md","scorecard_url":"https://app.decimal.ai/skills/tooluniverse-variant-to-mechanism"}