---
name: yogsoth-ai/heterogeneity-source-analysis
source: https://app.decimal.ai/s/yogsoth-ai-heterogeneity-source-analysis@1/SKILL.md
source_sha256: 632519aea669
---

# Heterogeneity Source Analysis SOP

Systematically identify, classify, and prioritize potential sources of between-study heterogeneity for investigation via subgroup analysis and meta-regression.

## When to Use

- When meta-analysis reveals substantial heterogeneity (I2 > 50%)
- During planning of subgroup analyses and meta-regression
- When assessing the transitivity assumption in network meta-analysis

## Input

- `study_characteristics`: Study-level characteristics and covariates
- `effect_sizes`: Extracted effect sizes showing variation
- `moderator_candidates`: Pre-specified candidate moderator variables

## Output

Classified sources of heterogeneity with investigation priority and statistical analysis plan.

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## Available SOPs

Optional, no fixed order; the final leaf is always a sop.

| SOP | When to use |
| --- | --- |
| spawn-agent | Spawn a customized CC subagent with full MCP tool access. Used by SOPs that declare execution: subagent. |

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