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OpenClaw bioinformatics skill library for genomics pipelines
Passed 20 of 24 test cases with the skill, and 14 of 24 without it.
and 5 more in the full report
7 fixed13 passed either way3 still failing1 broke
Tokens, turns and time describe resource use, not a dollar price.
One of 7 test cases the skill fixed. Same model, same prompt, with and without the skill.
For transcript abundance quantification under clawbio.tools in openclaw.config.json, a user proposes setting quantifier to "kallisto". What default quantifier tool is defined in the ClawBio configuration?
| Checked | Without skill | With skill |
|---|---|---|
| The configuration specifies "featurecounts" as the quantifier tool. | Missed | Passed |
The instructions your model reads when the skill loads.
ClawBio is a bioinformatics skill library for OpenClaw that provides pre-built skills for common genomics and biological analysis tasks — sequence alignment, variant calling, differential expression, pathway analysis, and more. Each skill encapsulates best-practice bioinformatics pipelines as conversational agent capabilities, making complex analyses accessible through natural language.
# Install as OpenClaw plugin
openclaw plugins install @clawbio/clawbio
# Or add to your OpenClaw configuration
# In openclaw.config.json:
{
"plugins": ["@clawbio/clawbio"]
}
| Skill | Pipeline | Description |
|---|---|---|
| sequence-align | BWA/Bowtie2 | Align reads to reference genome |
| variant-call | GATK/BCFtools | Call SNPs and indels |
| rna-seq | STAR + DESeq2 | Differential expression analysis |
| chip-seq | MACS2 + DiffBind | Peak calling and differential binding |
| metagenomics | Kraken2 + Bracken | Taxonomic classification |
| phylogenetics | IQ-TREE + RAxML | Phylogenetic tree construction |
| protein-structure | AlphaFold/ESMFold | Structure prediction |
| pathway-analysis | GSEA + enrichR | Gene set enrichment |
# Through OpenClaw conversational interface:
# "Analyze differential expression between treated and control
# samples in the data/rnaseq/ directory"
test cases passed, vs 14 / 24 without
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