Journal Of The American Society Of Nephrology

Journal of the American Society of Nephrology (journal-of-the-american-society-of-nephrology)

Journal positioning

The Journal of the American Society of Nephrology (JASN) is the American Society of Nephrology flagship, publishing high-impact nephrology research across the full evidence spectrum: clinical trials and cohorts in kidney disease, dialysis, and transplantation; translational kidney biomarker and -omics work; and basic renal physiology, cell biology, and disease-mechanism science. Its defining expectation is a mechanistically or clinically significant advance in kidney health and disease, with an emphasis on discovery and disease mechanism alongside rigorous clinical work — not a small single-center series or a descriptive registry slice. With its U.S. society base, JASN often anchors strongly in mechanism, novel biology, and trials that move nephrology practice. This skill is a fit / venue-selection / re-framing aid; it is not clinical or regulatory advice and does not replace the journal's current instructions for authors. Before submitting, re-check the live JASN author instructions.

When to trigger

• The author names JASN for a nephrology clinical, translational, or basic-science study and wants a fit/framing check.
• A kidney study must be re-framed around a disease mechanism or a practice-changing nephrology question rather than a descriptive report.
• The author is choosing between JASN and Kidney International (ISN flagship), or between JASN and general medicine.
• The author needs the journal's reporting-guideline, registration, and basic/animal-study expectations for kidney research.

Scope & topic fit

• Chronic and acute kidney disease: CKD progression, AKI, glomerular and tubulointerstitial disease, and diabetic and hypertensive kidney disease.
• Dialysis and renal replacement: hemodialysis, peritoneal dialysis, and outcomes/access research.
• Kidney transplantation: immunology, rejection, allograft outcomes, and organ-preservation science.
• Renal physiology and cell biology: tubular transport, podocyte and glomerular biology, fibrosis, and electrolyte/acid-base mechanism.
• Translational nephrology: kidney biomarkers, genetics/genomics, single-cell and -omics atlases with disease relevance.