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🎚️ gi-enhancer · clawbio | DecimalAI

scienceby clawbio

🎚️ gi-enhancer

clawbio/gi-enhancer

Source clawbio/clawbio ↗License NOASSERTION

Predict enhancer activity in DNA sequences using the Genomic Intelligence G0 DeepSTARR model, via the hosted /v1/tasks/enhancer/predict API. Returns per-window activity scores.

SkillScore82Maintained

Automatic

Research pack

Last verified 8/28/2026

What it changes

Passed 16 of 19 test cases with the skill, and 5 of 19 without it.

Without skill27%

With skill82%

Checks it passed that the model alone missed

Includes command.sh in the reproducibility folder output.
Includes environment.json in the reproducibility folder output.
Specifies GET /v1/tasks/enhancer/models as the listing endpoint.

and 10 more in the full report

12 fixed6 passed either way4 still failing0 broke

Pass-rate lift: +55 pp
Tokens: +9%
Agent turns: 0%
Response time: -54%

Model gemini-3.6-flashMeasured 8/28/2026v218 of 22 cases passed with skill · 19 comparable

Tokens, turns and time describe resource use, not a dollar price.

Use this skill

Save it into your project's skills folder. Claude Code picks it up in its next session.

curl -fsSL --create-dirs -o .claude/skills/clawbio-gi-enhancer/SKILL.md https://app.decimal.ai/s/clawbio-gi-enhancer/SKILL.md

Want it pinned and updatable? pip install "decimalai>=0.15", then decimalai skills add clawbio-gi-enhancer, and start Claude Code with claude --plugin-dir "$(git rev-parse --show-toplevel)/.agents"

1 · One-time — install the CLI (docs ↗)

pip install "decimalai>=0.15"

2 · Get the skill — writes .agents/skills/clawbio-gi-enhancer/ and pins it in .decimal/skills.lock

decimalai skills add clawbio-gi-enhancer

No CLI? Get the same file — curl · raw file

curl -fsSL --create-dirs -o .claude/skills/clawbio-gi-enhancer/SKILL.md https://app.decimal.ai/s/clawbio-gi-enhancer/SKILL.md

Raw file: /s/clawbio-gi-enhancer/SKILL.md ↗ · machine-readable summary at /s/clawbio-gi-enhancer.json ↗

Safety checks: 3 of 3 passed

Code scan CleanIntent PassedContent Clean

See it in action

One of 12 test cases the skill fixed. Same model, same prompt, with and without the skill.

1 of 12

Prompt

If both a CLI argument and an environment variable exist for authorization when running enhancer scoring, which token value takes precedence?

What was checked, without and with the skill
Checked	Without skill	With skill
States that the explicit --api-key CLI flag takes precedence over the GI_API_KEY environment variable.	Missed	Passed

case-12 · gemini-3.6-flash · 8/28/2026 · answers are capped and redacted

What's inside

The instructions your model reads when the skill loads.

SKILL.md108 linessingle file

🎚️ gi-enhancer

You are gi-enhancer, a ClawBio agent that calls the Genomic Intelligence enhancer-activity model. Given a sequence, it returns per-window activity predictions, in ~1 s via the hosted API.

⚠️ Remote inference — opt-in required. Unlike most ClawBio skills, this skill uploads your FASTA sequence to the hosted Genomic Intelligence API at https://api.genomicintelligence.ai. The same models also run interactively at https://genomicintelligence.ai. Do not submit identifiable patient data without an appropriate data-use agreement. Key setup: see Authentication below.

Trigger

Fire this skill when the user says any of:

"predict enhancer activity"
"score this for enhancer / CRE / regulatory function"
"is this an enhancer?"
"DeepSTARR prediction", "STARR-seq prediction"
"gi-enhancer"
"predict cis-regulatory activity"

Do NOT fire when:

The user asks for promoter activity → gi-promoter
The user asks for chromatin state / accessibility → gi-chromatin

Why This Exists

Without it: DeepSTARR-style local inference requires Keras + GPU + tokenization knowhow.
With it: One CLI call → per-window activity scores in ~1 s.
Why ClawBio: Hosted G0 DeepSTARR plus ClawBio reproducibility + orchestrator routing.

API Backed

POST https://api.genomicintelligence.ai/v1/tasks/enhancer/predict. Omit model and the API resolves the default — a DeepSTARR model trained on Drosophila S2 cells. GET /v1/tasks/enhancer/models is the current list.

Contract note. The Genomic Intelligence API publishes one operation per task, each with its own request schema: per-task minLength/maxLength on sequence, and a typed, closed options object (an unknown option key is a 422 validation_failed, not a silent ignore). The bounds quoted in this file are the published ones, but the authority is always the served schema: GET https://api.genomicintelligence.ai/v1/openapi.json.

Workflow

Parse: single-record FASTA.
POST to /v1/tasks/enhancer/predict; the API windows internally.
Render: report.md + result.json + reproducibility/.

CLI Reference

Track record

Benchmark

16 / 19

test cases passed, vs 5 / 19 without

Adoption

Users: 0
Times used: 0

Safety and source details

SkillSafety

✓ 3 of 3 passed

Code scan15 of 15 checks clean

0 critical · 0 warning · 0 info — scanner v5 — 8/25/2026

View 15 scanner checks

live_secretremote_code_executionreverse_shelldata_exfiltrationssrf_metadataagent_snoopinganti_refusaldestructive_commandsobfuscated_unicodeunicode_homoglyphopaque_blobsuspicious_urltool_overreachtrigger_abuseprompt_injection_phrasing

IntentSafe

LLM judge · does the skill do what it claims

ContentClean

LLM judge · policy & harmful-content review

Source

Imported

clawbio / clawbio

skills/gi-enhancer/SKILL.md

View on GitHub ↗

License MITImported 8/25/2026Version v2

Other skills for the same job

Published skills whose descriptions closely match this one, with their headline benchmark lift.

clawbio/gi-chromatinPredict chromatin state — histone marks, DNase, TF binding — across 919 tracks (DeepSEA-style) for DNA sequences, via the hosted Genomic Intelligence /v1/tasks/chromatin/predict API.Close match+55 pp pass-rate lift

More skills from the same source and nearby in the registry, with their headline benchmark lift.

Ready to supercharge your AI agents?

See it in action

What's inside

🎚️ gi-enhancer

Trigger

Why This Exists

API Backed

Workflow

CLI Reference

Track record

Benchmark

Adoption

SkillSafety

Source

Other skills for the same job

Related skills