Informe Clinico WES en Espanol

Informe Clinico WES en Espanol

Skill for generating professional clinical PDF reports in Spanish from whole exome sequencing (WES) data. Designed for Novogene WES data (GATK + ANNOVAR pipeline) but adaptable to any WES pipeline with equivalent annotations. Translates all section headings, table headers, cell values, and interpretive text from English markdown input to Spanish PDF output.

Trigger

Fire this skill when the user says any of:

• "informe clinico WES"
• "generar informe exoma en espanol"
• "clinical report in Spanish"
• "Novogene report Spanish"
• "exome PDF report Spanish"
• "Predice/Inbiomedic report"

Do NOT fire when:

• User asks for an English report (use wes-clinical-report-en)
• User asks for variant annotation only (use variant-annotation)
• User asks for ACMG classification only (use clinical-variant-reporter)

Scope

One skill, one task: convert WES markdown reports (English input) into professional Spanish-language clinical PDFs with full translation and clinical interpretation.

Workflow

1. Parse WES markdown report (structured sections 1-7)
2. Extract KPI metrics from Exome Summary
3. Extract pathogenic variants, PGx alerts, rare damaging variants
4. Translate all headings, table headers, cell values, and body text to Spanish
5. Build interpretive summary paragraph in Spanish
6. Render all sections as styled PDF with clinical tables
7. Add ancestry estimation (section 8) if data available
8. Add limitations section (section 9) in Spanish