Benchling R&D Python SDK: CRUD on registry entities (DNA, RNA, proteins, custom), inventory, ELN, workflow automation. Needs Benchling account and API key. Use biopython for local sequence analysis; pubchem for chemical DBs.
SkillScore100Maintained
Automatic
◆Research pack
Last verified 8/23/2026
What it changes
Passed 25 of 25 test cases with the skill, and 14 of 25 without it.
Without skill56%
With skill100%
Checks it passed that the model alone missed
The script passes interval_wait_seconds set to 3.
The script catches BenchlingError exception class.
The script imports RetryStrategy from benchling_sdk.retry.
and 12 more in the full report
11 fixed14 passed either way0 still failing0 broke
Pass-rate lift
+44 pp
Tokens
+181%
Agent turns
0%
Response time
-32%
Model gemini-3.6-flashMeasured 8/23/2026v125 of 25 cases passed with skill
Tokens, turns and time describe resource use, not a dollar price.
See it in action
One of 11 test cases the skill fixed. Same model, same prompt, with and without the skill.
1 of 11
Prompt
Write a Python snippet to create a circular DNA sequence in Benchling named 'pUC19-GFP' with bases 'ATCGATCG' in folder 'fld_123' under schema 'ts_plasmid'. Pass custom schema field 'gene_name' as 'GFP'. Avoid raw dictionaries for custom schema fields.
What was checked, without and with the skill
Checked
Without skill
With skill
The script wraps custom schema fields with benchling.models.fields.
Missed
Passed
The script sets is_circular to True.
Passed
Passed
case-07 · gemini-3.6-flash · 8/23/2026 · answers are capped and redacted
What's inside
The instructions your model reads when the skill loads.
SKILL.md505 linessingle file
Benchling Integration — R&D Platform SDK
Overview
Benchling is a cloud platform for life sciences R&D. The Python SDK provides programmatic access to registry entities (DNA, proteins), inventory, electronic lab notebooks, and workflows. All operations require a Benchling tenant URL and API key or OAuth credentials.
When to Use
Creating, updating, or querying biological sequences (DNA, RNA, proteins) in Benchling registry