Install any skill in seconds. Free to start, no credit card required.
Get Started Free →Cancer treatment recommendations from molecular profile (mutations + cancer type + biomarkers) — FDA-approved + investigational therapies, resistance mechanisms, matching clinical trials, prognosis. Uses CIViC, ClinVar, OpenTargets, ClinicalTrials.gov.
3/3 safety checks passed
3 of 22 test cases passed with the skill.
Lift withheld: 3 comparable cases; this report requires 8.
Adds every file the skill has, pinned so you can update it. No account needed.
pip install "decimalai>=0.15"
decimalai skills add mims-harvard-tooluniverse-precision-oncology
claude --plugin-dir "$(git rev-parse --show-toplevel 2>/dev/null || pwd)/.agents"The same install from Python, for a notebook or a setup script.
pip install "decimalai>=0.15"from decimalai import skillpkg
# Writes .agents/skills and .decimal/skills.toml. Safe to run twice.
result = skillpkg.add("mims-harvard-tooluniverse-precision-oncology")
if result.exit_code:
raise SystemExit(result.problems)
print("Added. Start Claude Code with the command below.")claude --plugin-dir "$(git rev-parse --show-toplevel 2>/dev/null || pwd)/.agents"Type these in a Claude Code session. No account or API key. It writes the skill and any files it bundles, and asks first when its safety rating isn't Passed.
/plugin marketplace add decimal-labs/decimalai-claude-plugins
/plugin install decimalai@decimalai/decimalai:install mims-harvard-tooluniverse-precision-oncologyThe plugin needs python3 and curl on your machine.
No Python or account. Claude Code picks it up in its next session.
curl -fsSL --create-dirs -o .claude/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.md https://app.decimal.ai/s/mims-harvard-tooluniverse-precision-oncology/SKILL.md.claude/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.mdThis gets SKILL.md only. The skill's 1 other file is not included.
agent_config() hands your agent the skill. With no DecimalAI key it reads your project's files and sends nothing. Needs SDK 0.27 or newer.
pip install "decimalai[claude-agent-sdk]"
decimalai skills add mims-harvard-tooluniverse-precision-oncologyimport asyncio
from claude_agent_sdk import ClaudeAgentOptions
from decimalai.claude_agent_sdk import agent_config
# With no DECIMAL_API_KEY this reads the skills your project lists, from disk.
support = agent_config("support", fallback="You are a helpful agent.")
async def main():
question = "Hello!"
async with support.run(question) as run: # one user message, one run
async for message in run.query(options=ClaudeAgentOptions(max_turns=6)):
print(message)
# In a notebook or async code: await main()
asyncio.run(main())Prefer its own loader? ClaudeAgentOptions(plugins=[skills_plugin()], skills="all") reads the same folder. Use one or the other: a skill delivered both ways reaches the prompt twice.
The same install from Python, for a notebook or a setup script. agent_config() hands your agent the skill. With no DecimalAI key it reads your project's files and sends nothing. Needs SDK 0.27 or newer.
pip install "decimalai[claude-agent-sdk]"from decimalai import skillpkg
# Writes .agents/skills and .decimal/skills.toml. Safe to run twice.
result = skillpkg.add("mims-harvard-tooluniverse-precision-oncology")
if result.exit_code:
raise SystemExit(result.problems)
import asyncio
from claude_agent_sdk import ClaudeAgentOptions
from decimalai.claude_agent_sdk import agent_config
# With no DECIMAL_API_KEY this reads the skills your project lists, from disk.
support = agent_config("support", fallback="You are a helpful agent.")
async def main():
question = "Hello!"
async with support.run(question) as run: # one user message, one run
async for message in run.query(options=ClaudeAgentOptions(max_turns=6)):
print(message)
# In a notebook or async code: await main()
asyncio.run(main())Prefer its own loader? ClaudeAgentOptions(plugins=[skills_plugin()], skills="all") reads the same folder. Use one or the other: a skill delivered both ways reaches the prompt twice.
No DecimalAI package. The whole skill goes in every prompt, and nothing pins or updates it.
.agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.mdimport asyncio
from pathlib import Path
from claude_agent_sdk import ClaudeAgentOptions, query
skill = Path(".agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.md").read_text()
options = ClaudeAgentOptions(system_prompt=f"You are a helpful agent.\n\n{skill}", max_turns=6)
async def main():
async for message in query(prompt="Hello!", options=options):
print(message)
# In a notebook or async code: await main()
asyncio.run(main())This gets SKILL.md only. The skill's 1 other file is not included.
agent_config() hands your agent the skill. With no DecimalAI key it reads your project's files and sends nothing. Needs SDK 0.27 or newer.
pip install "decimalai[openai-agents]"
decimalai skills add mims-harvard-tooluniverse-precision-oncologyfrom agents import Agent, Runner
from decimalai.openai_agents import agent_config
# With no DECIMAL_API_KEY this reads the skills your project lists, from disk.
support = agent_config("support", fallback="You are a helpful agent.")
agent = Agent(
name=support.name,
instructions=support.instructions, # your prompt, then the skill list
tools=[*support.tools], # your tools, then load_skill
)
# In a notebook or async code: result = await Runner.run(agent, "Hello!")
result = Runner.run_sync(agent, "Hello!")Using SandboxAgent? capabilities=[Shell(), decimalai.openai_agents.sandbox_skills()] points its own loader at the same folder.
The same install from Python, for a notebook or a setup script. agent_config() hands your agent the skill. With no DecimalAI key it reads your project's files and sends nothing. Needs SDK 0.27 or newer.
pip install "decimalai[openai-agents]"from decimalai import skillpkg
# Writes .agents/skills and .decimal/skills.toml. Safe to run twice.
result = skillpkg.add("mims-harvard-tooluniverse-precision-oncology")
if result.exit_code:
raise SystemExit(result.problems)
from agents import Agent, Runner
from decimalai.openai_agents import agent_config
# With no DECIMAL_API_KEY this reads the skills your project lists, from disk.
support = agent_config("support", fallback="You are a helpful agent.")
agent = Agent(
name=support.name,
instructions=support.instructions, # your prompt, then the skill list
tools=[*support.tools], # your tools, then load_skill
)
# In a notebook or async code: result = await Runner.run(agent, "Hello!")
result = Runner.run_sync(agent, "Hello!")Using SandboxAgent? capabilities=[Shell(), decimalai.openai_agents.sandbox_skills()] points its own loader at the same folder.
No DecimalAI package. The whole skill goes in every prompt, and nothing pins or updates it.
.agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.mdfrom pathlib import Path
from agents import Agent, Runner
skill = Path(".agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.md").read_text()
agent = Agent(name="support", instructions=f"You are a helpful agent.\n\n{skill}")
# In a notebook or async code: result = await Runner.run(agent, "Hello!")
result = Runner.run_sync(agent, "Hello!")This gets SKILL.md only. The skill's 1 other file is not included.
agent_config() hands your agent the skill. With no DecimalAI key it reads your project's files and sends nothing. Needs SDK 0.27 or newer.
pip install "decimalai[openai]"
decimalai skills add mims-harvard-tooluniverse-precision-oncologyimport json
from openai import OpenAI
from decimalai.openai import agent_config
client = OpenAI()
# With no DECIMAL_API_KEY this reads the skills your project lists, from disk.
support = agent_config("support", fallback="You are a helpful agent.")
def lookup_order(order_id: str) -> str:
return f"Order {order_id} shipped yesterday."
# Your tools, as Chat Completions takes them, and what answers each.
TOOLS = [{"type": "function", "function": {
"name": "lookup_order",
"description": "Look up the status of an order.",
"parameters": {"type": "object", "properties": {"order_id": {"type": "string"}},
"required": ["order_id"]},
}}]
FUNCTIONS = {"lookup_order": lookup_order}
question = "Where is order A1001?"
with support.run(question) as run: # one user message, one run
# run.system is your prompt, then the skill list.
messages = [{"role": "system", "content": run.system}, run.message]
while True:
reply = client.chat.completions.create(
model="gpt-5.4-mini",
messages=messages,
tools=[*TOOLS, *run.tools], # your tools, then load_skill
).choices[0].message
messages.append(reply)
if not reply.tool_calls:
break
for call in reply.tool_calls:
# load_skill is answered by the run; your own tools by FUNCTIONS.
function = FUNCTIONS.get(call.function.name)
messages.append(run.tool_result(call) or {
"role": "tool", "tool_call_id": call.id,
"content": function(**json.loads(call.function.arguments)) if function
else f"There is no tool named {call.function.name!r}.",
})
print(reply.content)
# The Responses API takes run.response_tools instead of run.tools.The same install from Python, for a notebook or a setup script. agent_config() hands your agent the skill. With no DecimalAI key it reads your project's files and sends nothing. Needs SDK 0.27 or newer.
pip install "decimalai[openai]"from decimalai import skillpkg
# Writes .agents/skills and .decimal/skills.toml. Safe to run twice.
result = skillpkg.add("mims-harvard-tooluniverse-precision-oncology")
if result.exit_code:
raise SystemExit(result.problems)
import json
from openai import OpenAI
from decimalai.openai import agent_config
client = OpenAI()
# With no DECIMAL_API_KEY this reads the skills your project lists, from disk.
support = agent_config("support", fallback="You are a helpful agent.")
def lookup_order(order_id: str) -> str:
return f"Order {order_id} shipped yesterday."
# Your tools, as Chat Completions takes them, and what answers each.
TOOLS = [{"type": "function", "function": {
"name": "lookup_order",
"description": "Look up the status of an order.",
"parameters": {"type": "object", "properties": {"order_id": {"type": "string"}},
"required": ["order_id"]},
}}]
FUNCTIONS = {"lookup_order": lookup_order}
question = "Where is order A1001?"
with support.run(question) as run: # one user message, one run
# run.system is your prompt, then the skill list.
messages = [{"role": "system", "content": run.system}, run.message]
while True:
reply = client.chat.completions.create(
model="gpt-5.4-mini",
messages=messages,
tools=[*TOOLS, *run.tools], # your tools, then load_skill
).choices[0].message
messages.append(reply)
if not reply.tool_calls:
break
for call in reply.tool_calls:
# load_skill is answered by the run; your own tools by FUNCTIONS.
function = FUNCTIONS.get(call.function.name)
messages.append(run.tool_result(call) or {
"role": "tool", "tool_call_id": call.id,
"content": function(**json.loads(call.function.arguments)) if function
else f"There is no tool named {call.function.name!r}.",
})
print(reply.content)
# The Responses API takes run.response_tools instead of run.tools.No DecimalAI package. The whole skill goes in every prompt, and nothing pins or updates it.
.agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.mdfrom pathlib import Path
from openai import OpenAI
client = OpenAI()
skill = Path(".agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.md").read_text()
reply = client.chat.completions.create(
model="gpt-5.4-mini",
messages=[
{"role": "system", "content": f"You are a helpful agent.\n\n{skill}"},
{"role": "user", "content": "Hello!"},
],
).choices[0].messageThis gets SKILL.md only. The skill's 1 other file is not included.
agent_config() hands your agent the skill. With no DecimalAI key it reads your project's files and sends nothing. Needs SDK 0.27 or newer.
pip install "decimalai[anthropic]"
decimalai skills add mims-harvard-tooluniverse-precision-oncologyimport anthropic
from decimalai.anthropic import agent_config
client = anthropic.Anthropic()
# With no DECIMAL_API_KEY this reads the skills your project lists, from disk.
support = agent_config("support", fallback="You are a helpful agent.")
question = "Hello!"
with support.run(question) as run: # one user message, one run
answer = client.beta.messages.tool_runner(
model="claude-haiku-5-5",
max_tokens=4096,
system=run.system, # your prompt, then the skill list
tools=[*run.tools], # your tools, then load_skill
messages=[{"role": "user", "content": question}],
).until_done()The same install from Python, for a notebook or a setup script. agent_config() hands your agent the skill. With no DecimalAI key it reads your project's files and sends nothing. Needs SDK 0.27 or newer.
pip install "decimalai[anthropic]"from decimalai import skillpkg
# Writes .agents/skills and .decimal/skills.toml. Safe to run twice.
result = skillpkg.add("mims-harvard-tooluniverse-precision-oncology")
if result.exit_code:
raise SystemExit(result.problems)
import anthropic
from decimalai.anthropic import agent_config
client = anthropic.Anthropic()
# With no DECIMAL_API_KEY this reads the skills your project lists, from disk.
support = agent_config("support", fallback="You are a helpful agent.")
question = "Hello!"
with support.run(question) as run: # one user message, one run
answer = client.beta.messages.tool_runner(
model="claude-haiku-5-5",
max_tokens=4096,
system=run.system, # your prompt, then the skill list
tools=[*run.tools], # your tools, then load_skill
messages=[{"role": "user", "content": question}],
).until_done()No DecimalAI package. The whole skill goes in every prompt, and nothing pins or updates it.
.agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.mdfrom pathlib import Path
import anthropic
client = anthropic.Anthropic()
skill = Path(".agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.md").read_text()
reply = client.messages.create(
model="claude-haiku-5-5",
max_tokens=4096,
system=f"You are a helpful agent.\n\n{skill}",
messages=[{"role": "user", "content": "Hello!"}],
)This gets SKILL.md only. The skill's 1 other file is not included.
agent_config() hands your agent the skill. With no DecimalAI key it reads your project's files and sends nothing. Needs SDK 0.27 or newer.
pip install "decimalai[google-genai]"
decimalai skills add mims-harvard-tooluniverse-precision-oncologyfrom google import genai
from google.genai import types
from decimalai.google_genai import agent_config
client = genai.Client()
# With no DECIMAL_API_KEY this reads the skills your project lists, from disk.
support = agent_config("support", fallback="You are a helpful agent.")
def lookup_order(order_id: str) -> str:
return f"Order {order_id} shipped yesterday."
# Your functions, as declarations for the model, and what answers each.
TOOLS = [{"function_declarations": [{
"name": "lookup_order",
"description": "Look up the status of an order.",
"parameters_json_schema": {"type": "object", "properties": {"order_id": {"type": "string"}},
"required": ["order_id"]},
}]}]
FUNCTIONS = {"lookup_order": lookup_order}
question = "Where is order A1001?"
with support.run(question) as run: # one user message, one run
config = types.GenerateContentConfig(
system_instruction=run.system, # your prompt, then the skill list
tools=[*TOOLS, *run.tool_params], # your functions, then load_skill
)
contents = [{"role": "user", "parts": [{"text": run.message}]}]
while True:
response = client.models.generate_content(
model="gemini-3.5-flash", contents=contents, config=config,
)
if not response.function_calls:
break
contents.append(response.candidates[0].content)
parts = []
for call in response.function_calls:
# load_skill is answered by the run; your own functions by FUNCTIONS.
# A loop of your own rather than automatic function calling, which
# raises KeyError when the model asks for a function you did not pass.
function = FUNCTIONS.get(call.name)
parts.append(run.tool_result(call) or {"function_response": {
"name": call.name, "id": call.id,
"response": {"result": function(**(call.args or {})) if function
else f"There is no function named {call.name!r}."},
}})
contents.append({"role": "user", "parts": parts})
print(response.text)The same install from Python, for a notebook or a setup script. agent_config() hands your agent the skill. With no DecimalAI key it reads your project's files and sends nothing. Needs SDK 0.27 or newer.
pip install "decimalai[google-genai]"from decimalai import skillpkg
# Writes .agents/skills and .decimal/skills.toml. Safe to run twice.
result = skillpkg.add("mims-harvard-tooluniverse-precision-oncology")
if result.exit_code:
raise SystemExit(result.problems)
from google import genai
from google.genai import types
from decimalai.google_genai import agent_config
client = genai.Client()
# With no DECIMAL_API_KEY this reads the skills your project lists, from disk.
support = agent_config("support", fallback="You are a helpful agent.")
def lookup_order(order_id: str) -> str:
return f"Order {order_id} shipped yesterday."
# Your functions, as declarations for the model, and what answers each.
TOOLS = [{"function_declarations": [{
"name": "lookup_order",
"description": "Look up the status of an order.",
"parameters_json_schema": {"type": "object", "properties": {"order_id": {"type": "string"}},
"required": ["order_id"]},
}]}]
FUNCTIONS = {"lookup_order": lookup_order}
question = "Where is order A1001?"
with support.run(question) as run: # one user message, one run
config = types.GenerateContentConfig(
system_instruction=run.system, # your prompt, then the skill list
tools=[*TOOLS, *run.tool_params], # your functions, then load_skill
)
contents = [{"role": "user", "parts": [{"text": run.message}]}]
while True:
response = client.models.generate_content(
model="gemini-3.5-flash", contents=contents, config=config,
)
if not response.function_calls:
break
contents.append(response.candidates[0].content)
parts = []
for call in response.function_calls:
# load_skill is answered by the run; your own functions by FUNCTIONS.
# A loop of your own rather than automatic function calling, which
# raises KeyError when the model asks for a function you did not pass.
function = FUNCTIONS.get(call.name)
parts.append(run.tool_result(call) or {"function_response": {
"name": call.name, "id": call.id,
"response": {"result": function(**(call.args or {})) if function
else f"There is no function named {call.name!r}."},
}})
contents.append({"role": "user", "parts": parts})
print(response.text)No DecimalAI package. The whole skill goes in every prompt, and nothing pins or updates it.
.agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.mdfrom pathlib import Path
from google import genai
from google.genai import types
client = genai.Client()
skill = Path(".agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.md").read_text()
response = client.models.generate_content(
model="gemini-3.5-flash",
contents="Hello!",
config=types.GenerateContentConfig(system_instruction=f"You are a helpful agent.\n\n{skill}"),
)This gets SKILL.md only. The skill's 1 other file is not included.
agent_config() hands your agent the skill. With no DecimalAI key it reads your project's files and sends nothing. Needs SDK 0.27 or newer.
pip install "decimalai[langchain]" langchain-openai
decimalai skills add mims-harvard-tooluniverse-precision-oncologyfrom langchain.agents import create_agent
from decimalai.langchain import agent_config
# With no DECIMAL_API_KEY this reads the skills your project lists, from disk.
support = agent_config("support", fallback="You are a helpful agent.")
agent = create_agent(
"openai:gpt-5.4-mini",
tools=[], # your tools; the middleware adds load_skill
middleware=[support.middleware], # your prompt, the skill list and load_skill
)
result = agent.invoke({"messages": [{"role": "user", "content": "Hello!"}]})The same install from Python, for a notebook or a setup script. agent_config() hands your agent the skill. With no DecimalAI key it reads your project's files and sends nothing. Needs SDK 0.27 or newer.
pip install "decimalai[langchain]" langchain-openaifrom decimalai import skillpkg
# Writes .agents/skills and .decimal/skills.toml. Safe to run twice.
result = skillpkg.add("mims-harvard-tooluniverse-precision-oncology")
if result.exit_code:
raise SystemExit(result.problems)
from langchain.agents import create_agent
from decimalai.langchain import agent_config
# With no DECIMAL_API_KEY this reads the skills your project lists, from disk.
support = agent_config("support", fallback="You are a helpful agent.")
agent = create_agent(
"openai:gpt-5.4-mini",
tools=[], # your tools; the middleware adds load_skill
middleware=[support.middleware], # your prompt, the skill list and load_skill
)
result = agent.invoke({"messages": [{"role": "user", "content": "Hello!"}]})No DecimalAI package. The whole skill goes in every prompt, and nothing pins or updates it.
.agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.mdfrom pathlib import Path
from langchain.agents import create_agent
skill = Path(".agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.md").read_text()
agent = create_agent("openai:gpt-5.4-mini", tools=[], system_prompt=f"You are a helpful agent.\n\n{skill}")
result = agent.invoke({"messages": [{"role": "user", "content": "Hello!"}]})This gets SKILL.md only. The skill's 1 other file is not included.
CrewAI's own skill loader reads the installed folder. No DecimalAI account needed.
pip install "decimalai>=0.16" "crewai>=1.15.27"
decimalai skills add mims-harvard-tooluniverse-precision-oncologyimport decimalai.crewai
from crewai import Agent, Crew, Task
agent = Agent(
role="Support", goal="Help the customer", backstory="A support agent.",
llm=llm, # your own CrewAI LLM
skills=decimalai.crewai.skills(), # the installed folder
tools=decimalai.crewai.skill_tools(), # reads a skill's files, runs its scripts
)
task = Task(description="Hello!", expected_output="an answer", agent=agent)
Crew(agents=[agent], tasks=[task]).kickoff()The same install from Python, for a notebook or a setup script. CrewAI's own skill loader reads the installed folder. No DecimalAI account needed.
pip install "decimalai>=0.16" "crewai>=1.15.27"from decimalai import skillpkg
# Writes .agents/skills and .decimal/skills.toml. Safe to run twice.
result = skillpkg.add("mims-harvard-tooluniverse-precision-oncology")
if result.exit_code:
raise SystemExit(result.problems)
import decimalai.crewai
from crewai import Agent, Crew, Task
agent = Agent(
role="Support", goal="Help the customer", backstory="A support agent.",
llm=llm, # your own CrewAI LLM
skills=decimalai.crewai.skills(), # the installed folder
tools=decimalai.crewai.skill_tools(), # reads a skill's files, runs its scripts
)
task = Task(description="Hello!", expected_output="an answer", agent=agent)
Crew(agents=[agent], tasks=[task]).kickoff()No DecimalAI package. CrewAI's own loader reads the folder, and nothing pins or updates it.
.agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.mdfrom pathlib import Path
from crewai import Agent, Crew, Task
agent = Agent(
role="Support", goal="Help the customer", backstory="A support agent.",
llm=llm, # your own CrewAI LLM
skills=[Path(".agents/skills")],
)
task = Task(description="Hello!", expected_output="an answer", agent=agent)
Crew(agents=[agent], tasks=[task]).kickoff()This gets SKILL.md only. The skill's 1 other file is not included.
agent_config() hands your agent the skill. With no DecimalAI key it reads your project's files and sends nothing. Needs SDK 0.27 or newer.
pip install "decimalai[adk]"
decimalai skills add mims-harvard-tooluniverse-precision-oncologyfrom decimalai.adk import DecimalAIPlugin, agent_config
from google.adk.agents import LlmAgent
from google.adk.apps import App
# With no DECIMAL_API_KEY this reads the skills your project lists, from disk.
support = agent_config("support", fallback="You are a helpful agent.")
agent = LlmAgent(
name="support", # ADK needs a Python identifier
model="gemini-3.5-flash",
instruction=support.instruction, # your prompt, then the skill list
tools=[*support.tools], # your tools, then load_skill
)
# DecimalAIPlugin makes each invocation of runners built from this App one trace.
app = App(name="support", root_agent=agent, plugins=[DecimalAIPlugin()])Prefer ADK's own loader? SkillToolset(skills=decimalai.adk.skills(), ...) reads the same folder. Use one or the other: a skill delivered both ways reaches the prompt twice.
The same install from Python, for a notebook or a setup script. agent_config() hands your agent the skill. With no DecimalAI key it reads your project's files and sends nothing. Needs SDK 0.27 or newer.
pip install "decimalai[adk]"from decimalai import skillpkg
# Writes .agents/skills and .decimal/skills.toml. Safe to run twice.
result = skillpkg.add("mims-harvard-tooluniverse-precision-oncology")
if result.exit_code:
raise SystemExit(result.problems)
from decimalai.adk import DecimalAIPlugin, agent_config
from google.adk.agents import LlmAgent
from google.adk.apps import App
# With no DECIMAL_API_KEY this reads the skills your project lists, from disk.
support = agent_config("support", fallback="You are a helpful agent.")
agent = LlmAgent(
name="support", # ADK needs a Python identifier
model="gemini-3.5-flash",
instruction=support.instruction, # your prompt, then the skill list
tools=[*support.tools], # your tools, then load_skill
)
# DecimalAIPlugin makes each invocation of runners built from this App one trace.
app = App(name="support", root_agent=agent, plugins=[DecimalAIPlugin()])Prefer ADK's own loader? SkillToolset(skills=decimalai.adk.skills(), ...) reads the same folder. Use one or the other: a skill delivered both ways reaches the prompt twice.
No DecimalAI package. The whole skill goes in every prompt, and nothing pins or updates it.
.agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.mdfrom pathlib import Path
from google.adk.agents import LlmAgent
skill = Path(".agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.md").read_text()
agent = LlmAgent(
name="support",
model="gemini-3.5-flash",
instruction=lambda context: f"You are a helpful agent.\n\n{skill}",
)This gets SKILL.md only. The skill's 1 other file is not included.
agent_config() hands your agent the skill. With no DecimalAI key it reads your project's files and sends nothing. Needs SDK 0.27 or newer.
pip install "decimalai[pydantic-ai]"
decimalai skills add mims-harvard-tooluniverse-precision-oncologyfrom pydantic_ai import Agent
from decimalai.pydantic_ai import agent_config
# With no DECIMAL_API_KEY this reads the skills your project lists, from disk.
support = agent_config("support", fallback="You are a helpful agent.")
agent = Agent(
"openai:gpt-4o-mini",
name=support.name,
tools=[], # your tools; the capability adds load_skill
capabilities=[support], # your prompt, the skill list and load_skill
)
# In a notebook or async code: result = await agent.run("Hello!")
result = agent.run_sync("Hello!")On the Pydantic AI harness, decimalai.pydantic_ai_harness.skills(project) uses its own loader instead.
The same install from Python, for a notebook or a setup script. agent_config() hands your agent the skill. With no DecimalAI key it reads your project's files and sends nothing. Needs SDK 0.27 or newer.
pip install "decimalai[pydantic-ai]"from decimalai import skillpkg
# Writes .agents/skills and .decimal/skills.toml. Safe to run twice.
result = skillpkg.add("mims-harvard-tooluniverse-precision-oncology")
if result.exit_code:
raise SystemExit(result.problems)
from pydantic_ai import Agent
from decimalai.pydantic_ai import agent_config
# With no DECIMAL_API_KEY this reads the skills your project lists, from disk.
support = agent_config("support", fallback="You are a helpful agent.")
agent = Agent(
"openai:gpt-4o-mini",
name=support.name,
tools=[], # your tools; the capability adds load_skill
capabilities=[support], # your prompt, the skill list and load_skill
)
# In a notebook or async code: result = await agent.run("Hello!")
result = agent.run_sync("Hello!")On the Pydantic AI harness, decimalai.pydantic_ai_harness.skills(project) uses its own loader instead.
No DecimalAI package. The whole skill goes in every prompt, and nothing pins or updates it.
.agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.mdfrom pathlib import Path
from pydantic_ai import Agent
skill = Path(".agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.md").read_text()
agent = Agent("openai:gpt-4o-mini", instructions=f"You are a helpful agent.\n\n{skill}")
# In a notebook or async code: result = await agent.run("Hello!")
result = agent.run_sync("Hello!")This gets SKILL.md only. The skill's 1 other file is not included.
Deep Agents' own skill loader reads the installed folder. No DecimalAI account needed.
pip install "decimalai>=0.16" deepagents
decimalai skills add mims-harvard-tooluniverse-precision-oncologyimport decimalai.deepagents
from deepagents import create_deep_agent
agent = create_deep_agent(model=model, **decimalai.deepagents.skills())
agent.invoke({"messages": [{"role": "user", "content": "Hello!"}]})The default backend reads files but has no shell. To run a skill's scripts, pass skills(backend=LocalShellBackend(...)).
The same install from Python, for a notebook or a setup script. Deep Agents' own skill loader reads the installed folder. No DecimalAI account needed.
pip install "decimalai>=0.16" deepagentsfrom decimalai import skillpkg
# Writes .agents/skills and .decimal/skills.toml. Safe to run twice.
result = skillpkg.add("mims-harvard-tooluniverse-precision-oncology")
if result.exit_code:
raise SystemExit(result.problems)
import decimalai.deepagents
from deepagents import create_deep_agent
agent = create_deep_agent(model=model, **decimalai.deepagents.skills())
agent.invoke({"messages": [{"role": "user", "content": "Hello!"}]})The default backend reads files but has no shell. To run a skill's scripts, pass skills(backend=LocalShellBackend(...)).
No DecimalAI package. The whole skill goes in every prompt, and nothing pins or updates it.
.agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.mdfrom pathlib import Path
from deepagents import create_deep_agent
skill = Path(".agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.md").read_text()
agent = create_deep_agent(model=model, system_prompt=f"You are a helpful agent.\n\n{skill}")
agent.invoke({"messages": [{"role": "user", "content": "Hello!"}]})This gets SKILL.md only. The skill's 1 other file is not included.
Its own skill loader reads the installed folder. No DecimalAI account needed.
pip install "decimalai>=0.16" agent-framework
decimalai skills add mims-harvard-tooluniverse-precision-oncologyimport asyncio
from agent_framework import Agent
from decimalai.agent_framework import skills
agent = Agent(client=client, instructions="You are a helpful agent.", context_providers=[skills()])
asyncio.run(agent.run("Hello!"))It caches skills by default, so restart the process after decimalai skills update.
The same install from Python, for a notebook or a setup script. Its own skill loader reads the installed folder. No DecimalAI account needed.
pip install "decimalai>=0.16" agent-frameworkfrom decimalai import skillpkg
# Writes .agents/skills and .decimal/skills.toml. Safe to run twice.
result = skillpkg.add("mims-harvard-tooluniverse-precision-oncology")
if result.exit_code:
raise SystemExit(result.problems)
import asyncio
from agent_framework import Agent
from decimalai.agent_framework import skills
agent = Agent(client=client, instructions="You are a helpful agent.", context_providers=[skills()])
asyncio.run(agent.run("Hello!"))It caches skills by default, so restart the process after decimalai skills update.
No DecimalAI package. The whole skill goes in every prompt, and nothing pins or updates it.
.agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.mdimport asyncio
from pathlib import Path
from agent_framework import Agent
skill = Path(".agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.md").read_text()
agent = Agent(client=client, instructions=f"You are a helpful agent.\n\n{skill}")
asyncio.run(agent.run("Hello!"))This gets SKILL.md only. The skill's 1 other file is not included.
Strands' own skill loader reads the installed folder. No DecimalAI account needed.
pip install "decimalai>=0.16" strands-agents
decimalai skills add mims-harvard-tooluniverse-precision-oncologyfrom decimalai.strands import skills
from strands import Agent
from strands.vended_tools import file_editor, shell
agent = Agent(
model=model, # always pass one: the default is Amazon Bedrock
system_prompt="You are a helpful agent.",
tools=[file_editor, shell],
plugins=[skills()],
)
agent("Hello!")Strands loads an agent's skills once, so build the agent again after decimalai skills update.
The same install from Python, for a notebook or a setup script. Strands' own skill loader reads the installed folder. No DecimalAI account needed.
pip install "decimalai>=0.16" strands-agentsfrom decimalai import skillpkg
# Writes .agents/skills and .decimal/skills.toml. Safe to run twice.
result = skillpkg.add("mims-harvard-tooluniverse-precision-oncology")
if result.exit_code:
raise SystemExit(result.problems)
from decimalai.strands import skills
from strands import Agent
from strands.vended_tools import file_editor, shell
agent = Agent(
model=model, # always pass one: the default is Amazon Bedrock
system_prompt="You are a helpful agent.",
tools=[file_editor, shell],
plugins=[skills()],
)
agent("Hello!")Strands loads an agent's skills once, so build the agent again after decimalai skills update.
No DecimalAI package. The whole skill goes in every prompt, and nothing pins or updates it.
.agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.mdfrom pathlib import Path
from strands import Agent
skill = Path(".agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.md").read_text()
agent = Agent(model=model, system_prompt=f"You are a helpful agent.\n\n{skill}")
agent("Hello!")This gets SKILL.md only. The skill's 1 other file is not included.
Adds every file the skill has, pinned so you can update it. Cursor, Copilot, Cline and Warp read this folder by themselves.
pip install "decimalai>=0.15"
decimalai skills add mims-harvard-tooluniverse-precision-oncologyNo Python or account. Cursor, Copilot, Cline and Warp read this folder by themselves.
curl -fsSL --create-dirs -o .agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.md https://app.decimal.ai/s/mims-harvard-tooluniverse-precision-oncology/SKILL.md.agents/skills/mims-harvard-tooluniverse-precision-oncology/SKILL.mdThis gets SKILL.md only. The skill's 1 other file is not included.
Give its text to your model as instructions. No account or package needed.
This gets SKILL.md only. The skill's 1 other file is not included.
Raw files: /s/mims-harvard-tooluniverse-precision-oncology/SKILL.md · /s/mims-harvard-tooluniverse-precision-oncology.json
Fetch the file and give its text to your model as instructions. No account or package needed.
curl -fsSL https://app.decimal.ai/s/mims-harvard-tooluniverse-precision-oncology/SKILL.mdcurl -fsSL https://app.decimal.ai/s/mims-harvard-tooluniverse-precision-oncology.jsonThis gets SKILL.md only. The skill's 1 other file is not included.
You don't need a DecimalAI account.
Saved prompts and skills, pinned versions, and traces of this skill in your runs. DecimalAI does not run your agent.
Claude Code reads files from your project, so DecimalAI config does not apply there.
On Claude Agent SDK: save the skill to an agent here, set DECIMAL_API_KEY, and the same code uses it with no command to run. Changes you save reach the next run with no redeploy.
On OpenAI Agents: save the skill to an agent here, set DECIMAL_API_KEY, and the same code uses it with no command to run. Changes you save reach the next run with no redeploy.
On OpenAI SDK: save the skill to an agent here, set DECIMAL_API_KEY, and the same code uses it with no command to run. Changes you save reach the next run with no redeploy.
On Anthropic: save the skill to an agent here, set DECIMAL_API_KEY, and the same code uses it with no command to run. Changes you save reach the next run with no redeploy.
On Gemini API: save the skill to an agent here, set DECIMAL_API_KEY, and the same code uses it with no command to run. Changes you save reach the next run with no redeploy.
On LangChain: save the skill to an agent here, set DECIMAL_API_KEY, and the same code uses it with no command to run. Changes you save reach the next run with no redeploy.
On CrewAI: set DECIMAL_API_KEY and add decimalai.init(crewai=True) to record runs and skill use. The skill version stays in your repo.
On Google ADK: save the skill to an agent here, set DECIMAL_API_KEY, and the same code uses it with no command to run. Changes you save reach the next run with no redeploy.
On Pydantic AI: save the skill to an agent here, set DECIMAL_API_KEY, and the same code uses it with no command to run. Changes you save reach the next run with no redeploy.
On Deep Agents: set DECIMAL_API_KEY and add decimalai.init(langchain=True) to record runs and skill use. The skill version stays in your repo.
On Microsoft Agent Framework: set DECIMAL_API_KEY and add decimalai.init(otel=True, agent_name="support") to record runs and skill use. The skill version stays in your repo.
On Strands: set DECIMAL_API_KEY and add decimalai.init(otel=True, agent_name="support") to record runs and skill use. The skill version stays in your repo.
Editors read files from your project, so DecimalAI config does not apply there.
Anywhere else: record a use with decimalai.log_skill_activation() inside a trace.
Provide actionable treatment recommendations for cancer patients based on their molecular profile using CIViC, ClinVar, OpenTargets, ClinicalTrials.gov, and structure-based analysis.
Treatment selection follows a strict evidence hierarchy: FDA-approved for this specific mutation in this cancer type ranks highest, followed by approval for this mutation in any cancer (tumor-agnostic), then active clinical trials, and finally off-label use. Skipping this hierarchy to recommend off-label therapies when an approved option exists is a clinical error. Always check current NCCN guidelines and recent literature, as approvals change rapidly — a drug that was investigational last year may now be first-line.
When looking up treatment for a specific mutation, search CIViC and OncoKB FIRST, not PubMed. These databases have curated evidence levels. PubMed is for when curated databases don't have the answer.
Biomarker-to-drug logic — When a biomarker is identified, the first-line targeted therapy follows established mappings. Always verify current approval status via OncoKB/CIViC, but use this as a starting framework:
Resistance mechanism reasoning — When a patient progresses on targeted therapy, distinguish primary resistance (never responded — check if the mutation was truly the driver, or if co-mutations like TP53/RB1 abrogate response) from acquired resistance (responded then progressed — on-target mutations or bypass activation). Common patterns:
civic_search_evidence_items with the drug name + "resistance", then PubMed_search_articles for recent mechanisms.OncoKB_annotate_variant and civic_search_variants; never assume approval status from memory.search_clinical_trials with the specific condition and mutation; do not cite trials from memory.civic_search_evidence_items and PubMed_search_articles; do not assume resistance pathways.GDC_get_mutation_frequency or cBioPortal_get_mutations; do not estimate prevalence.KEY PRINCIPLES:
| Tool | WRONG | CORRECT |
|---|---|---|
civic_get_variant | variant_name | variant_id (numeric, e.g., 4170) |
civic_get_evidence_item | variant_id | id (numeric) |
OpenTargets_* | ensemblID | ensemblId (camelCase) |
search_clinical_trials | disease | condition |
Input: Cancer type + Molecular profile (mutations, fusions, amplifications)
Phase 1: Profile Validation -> Resolve gene IDs (Ensembl, UniProt, ChEMBL)
Phase 2: Variant Interpretation -> CIViC, ClinVar, COSMIC, GDC/TCGA, DepMap, OncoKB, cBioPortal, HPA
Phase 2.5: Tumor Expression -> CELLxGENE cell-type expression, ChIPAtlas regulatory context
Phase 3: Treatment Options -> OpenTargets + DailyMed (approved), ChEMBL (off-label)
Phase 3.5: Pathway & Network -> KEGG/Reactome pathways, IntAct interactions
Phase 4: Resistance Analysis -> CIViC + PubMed + NvidiaNIM structure analysis
Phase 5: Clinical Trials -> ClinicalTrials.gov search + eligibility
Phase 5.5: Literature -> PubMed, BioRxiv/MedRxiv preprints, OpenAlex citations
Phase 6: Report Synthesis -> Executive summary + prioritized recommendations
MyGene_query_genes - Resolve gene to Ensembl IDUniProt_search - Get UniProt accessionChEMBL_search_targets - Get ChEMBL target IDcivic_search_variants / civic_get_variant - CIViC evidenceCOSMIC_get_mutations_by_gene / COSMIC_search_mutations - Somatic mutationsGDC_get_mutation_frequency / GDC_get_ssm_by_gene - TCGA patient dataGDC_get_gene_expression / GDC_get_cnv_data - Expression and CNVGDC_get_survival - Kaplan-Meier survival data by project and optional gene mutation filterGDC_get_clinical_data - TCGA clinical metadata (stage, vital status, treatment, demographics)Progenetix_cnv_search - Copy number variation biosamples by genomic region and cancer type (NCIt code)DepMap_get_gene_dependencies / PharmacoDB_get_experiments - Target essentialityOncoKB_annotate_variant / OncoKB_get_gene_info - ActionabilitycBioPortal_get_mutations / cBioPortal_get_cancer_studies - Cross-study dataHPA_search_genes_by_query / HPA_get_comparative_expression_by_gene_and_cellline - ExpressionCELLxGENE_get_expression_data / CELLxGENE_get_cell_metadata - Cell-type expressionOpenTargets_get_associated_drugs_by_target_ensemblID - Approved drugs (param: ensemblId, camelCase)DGIdb_get_drug_gene_interactions - Drug-gene interactions (param: genes as array, e.g., ["EGFR"]). Comprehensive; covers inhibitors, antibodies, and investigational agents.DailyMed_search_spls - FDA label detailsChEMBL_get_drug_mechanisms - Drug mechanismkegg_find_genes / kegg_get_gene_info - KEGG pathwaysreactome_disease_target_score - Reactome disease relevanceintact_get_interaction_network - Protein interactionscivic_search_evidence_items - Search by known resistance mutations individually (e.g., molecular_profile="EGFR C797S", molecular_profile="MET Amplification"). The significance field in results indicates Resistance/Sensitivity — filter on it after retrieval.PubMed_search_articles - Resistance literature (e.g., "osimertinib resistance C797S combination therapy")alphafold_get_prediction / get_diffdock_info - Structure-based analysis (AlphaFold for structure, DiffDock for docking)search_clinical_trials - Find trials (param: condition, NOT disease)get_clinical_trial_eligibility_criteria - Eligibility detailsYou MUST call FAERS for the leading approved drug before finalizing the report. A clinical brief without real-world adverse-event data is incomplete.
FAERS_search_adverse_event_reports — REQUIRED: call with medicinalproduct="<drug_name>" for at least the top 1-2 approved drugs. Report top 10 serious AEs + death count.FDA_get_warnings_and_cautions_by_drug_name — REQUIRED: boxed warnings + key precautions.FAERS_count_death_related_by_drug - Mortality signal for a drugCPIC_list_guidelines - Check for relevant PGx guidelines (e.g., DPYD for fluoropyrimidines in chemo regimens, UGT1A1 for irinotecan). No CPIC guidelines exist for EGFR TKIs.fda_pharmacogenomic_biomarkers - FDA-labeled PGx biomarkers for the drugOncoKB demo mode: Without
ONCOKB_API_TOKENenv var, OncoKB only covers BRAF, TP53, ROS1. For other genes (EGFR, KRAS, ALK, etc.), set the API key or use CIViC as the primary evidence source.
PubMed_search_articles - Published evidence (use limit, mindate, maxdate for date filtering)BioRxiv_list_recent_preprints / MedRxiv_get_preprint - Preprints (flag as NOT peer-reviewed)openalex_search_works - Citation analysisFor CYP interaction with cancer drugs, run: python3 skills/tooluniverse-drug-drug-interaction/scripts/pharmacology_ref.py --type cyp_substrate --drug drugname
Only when you call it by name. Your agent never loads it on its own. Use for tumor-board treatment recommendations, evidence-tiered actionability assessment, and FDA-precedent-driven therapy selection.
Published skills whose descriptions closely match this one, with their headline benchmark lift.
Skills that do similar work, with their headline benchmark lift.
From the same source and nearby in the catalogue.