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Get Started Free →Clinical lab-units harmonization.
Graded exposure for anxiety disorders: Fear hierarchy, SUDs scale, exposure planning and guidance. Psychoeducation only, not implementation.
Query and download public cancer imaging data from NCI Imaging Data Commons using idc-index. Use for accessing large-scale radiology (CT, MR, PET) and pathology datasets for AI training or research. No authentication required. Query by metadata, visualize in browser, check licenses.
EHR Chat Assistant
ICD-10-CM diagnosis coding: answers using ONLY the bundled authoritative reference (never recalls or invents the value), where a smaller model otherwise produces a plausible-wrong answer.
AI-powered multimodal diagnostic fusion integrating radiology imaging (CT/MRI/PET), digital pathology (WSI), genomics, and clinical data for comprehensive cancer diagnosis and treatment planning.
Genogram work: Recognizing and reflecting on family relationship patterns. Multigenerational perspective, genogram symbols, pattern recognition, and resources in family history.
Complete survival analysis library in Python. Handles right-censored data, Kaplan-Meier curves, and Cox regression. Standard for clinical trial analysis and epidemiology.
Acceptance & Commitment Therapy (ACT) according to Steven Hayes: Hexaflex model with the six core processes of psychological flexibility.
AI-powered bone marrow morphology analysis, cell classification, and hematologic disorder diagnosis using deep learning on aspirate and biopsy images.
AI-powered analysis of coagulation disorders, thrombosis risk prediction, anticoagulation management, and platelet function assessment using machine learning.
AI-powered myeloproliferative neoplasm monitoring for disease progression prediction, treatment response tracking, and transformation risk assessment in PV, ET, and myelofibrosis.
Monitor EHR, lab, pharmacy, and integration pipeline health — interface uptime, failed HL7/FHIR messages, stale data feeds, API error rates, response times, and security anomalies across clinical systems. Use daily or when systems seem slow or data seems stale.
Systemic and solution-focused methods: miracle question, scaling, exception exploration, circular questions, hypothetical questions, worsening questions, coping questions. Merged from solution-focused-therapy and systemic-questioning.
抓中国权威医学指南正文（CSCO / NCCN 中文版 / NMPA / CDE / NHC）并返回结构化"治疗推荐表"。当用户做中国市场的疾病调研、需要 I 级证据来源、或需要交叉验证治疗方案推荐是否符合 CSCO 指南时使用。v2 (2026-04-26)：Cite-or-Block 升级 — 加 sources_dir 参数完整存档原文 + locate_section_in_guideline 函数，与 citation-anchor-resolver 联动。Iron Law：locale=zh-CN+geo=CN 时本 skill 在 PubMed 召回之前必跑，所有治疗方案推荐必须命中指南 I 级 ≥ 1 个。Fetches Chinese authoritative clinical guidelines (CSCO, NCCN-zh, NMPA, CDE, NHC) and returns structured "treatment recommendation tables". MUST run before PubMed recall when locale=zh-
AI-powered analysis of hemoglobin disorders including sickle cell disease, thalassemias, and variant hemoglobins using HPLC, electrophoresis, and molecular data.
Motivational Interviewing (MI) according to Miller and Rollnick: OARS techniques, change talk, fostering readiness for change.
Cite-or-Block 架构的基石原子 skill。把报告里的 citation 锚点 (例如 [guideline:CSCO-2024-NSCLC:§5.5.2] / [pmid:12345678:abstract]) 解析为源文件片段,并核对事实声明里的关键词是否在引用源原文里出现。 Foundation atomic skill for the Cite-or-Block architecture. Resolves citation anchors (e.g. [guideline:CSCO-2024-NSCLC:§5.5.2] / [pmid:12345678:abstract]) to raw source text fragments, and verifies whether claim keywords actually appear in the cited source. 使用场景 / Use when: 1. 报告生成后要做 fact-check (resolve_citation + verify_claim_against_source) 2
Fundamentals of therapeutic communication: Active listening, mirroring, paraphrasing, open questions, and validation.
Solution-Focused Brief Therapy according to de Shazer and Berg: Miracle question, exception exploration, scaling, resource activation.
AI-powered design of targeted gene panels for clinical and research applications including cancer diagnostics, pharmacogenomics, and rare disease testing.
Given a newborn's five delivery-room findings described in prose — skin color, heart rate, reflex response to stimulation, muscle tone, and breathing effort — computes the total Apgar score (0-10) by scoring each of the five signs 0, 1, or 2 and summing them. Use when someone reports what a just-born infant looked like at the one- or five-minute check and wants the single vitality number. Do NOT use for estimating gestational age (Ballard/Dubowitz), respiratory distress scoring (Silverman-Andersen), adult vital-sign triage, or deciding resuscitation steps.
Prepare and validate research-only clinical decision-support evaluation, evidence-profile, cohort, survival, biomarker/model, privacy, and governance artifacts. Use for aggregate or synthetic research documentation and traceability—not patient care or live clinical operation.
Create safety-bounded draft structures and run local deterministic checks for clinical case, diagnostic, trial, safety, and aggregate research reports. Use only with synthetic, de-identified, or aggregate inputs and verified source-fact manifests; every output requires qualified review.
MBSR fundamentals, body scan, and breathing exercises. Evidence-based mindfulness techniques according to Jon Kabat-Zinn for everyday life.
Cognitive Behavioral Therapy: ABC model, automatic thoughts, identifying cognitive distortions, and keeping thought records.
AI-powered clonal hematopoiesis of indeterminate potential (CHIP) detection, risk stratification, and cardiovascular/malignancy risk prediction using genomic and clinical data.
Format and structurally validate local treatment-plan documentation after clinical decisions have already been supplied and verified by authorized licensed professionals. Use for source traceability, clinician-authored intervention records, goals and checkpoints, shared-decision records, reconciliation handoffs, and release gates—not for clinical decision-making.
Psychoeducation on depression, anxiety disorders, PTSD, bipolar disorder, schizophrenia, ADHD, and borderline. Knowledge sharing without diagnosis.
Plan, execute, and document validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP <1220>/<1225>/<1226>, ICH M10 bioanalytical, CLSI EP, or ISO/IEC 17025. Use for HPLC, LC-MS/MS, GC, CE, ICP-MS, dissolution, qNMR, qPCR, NIR, and ligand binding or cell-based assays whenever the question is whether a procedure is fit for its intended purpose. Triggers include "method validation", "analytical method validation", "AMV", "validation pro
Classifies genetic variants according to ACMG (American College of Medical Genetics) guidelines.
Evidence-based clinical decision support and diagnostic reasoning
Comprehensive variant annotation using bcftools annotate/csq, VEP, SnpEff, and ANNOVAR. Add database annotations, predict functional consequences, and assess clinical significance. Use when annotating variants with functional and clinical information.
Use pydicom to read, inspect, write, transform, and safely preflight local DICOM datasets and pixel data. Applies to DICOM metadata, transfer syntaxes, compression plugins, frames, private elements, JSON, and bounded de-identification review.
AI-powered analysis for predicting optimal immune checkpoint inhibitor combinations based on tumor microenvironment, biomarkers, and molecular profiling.
Cite-or-Block 架构下的药名 cross-check 原子 skill。给定报告文本与 .cache/<slug>/sources/,扫描每个药品提及 → 找最近 citation 锚点 → 核对锚点指向的源里是否真的提到了此药(通用名 + 商品名)。无字典、无 fallback、源里没 = critical。
Trauma psychoeducation: Trauma definition, normal reactions, window of tolerance, trigger management, and self-care.
分析口腔健康数据、识别口腔问题模式、评估口腔健康状况、提供个性化口腔健康建议。支持与营养、慢性病、用药等其他健康数据的关联分析。
Radiology Reporter
Joint genotype calling across multiple samples using GATK CombineGVCFs and GenotypeGVCFs. Essential for cohort studies, population genetics, and leveraging VQSR. Use when performing joint genotyping across multiple samples.
Build clinical/healthcare deep-learning pipelines with PyHealth — loading EHR/signal/imaging datasets (MIMIC-III/IV, eICU, OMOP, SleepEDF, ChestXray14, EHRShot), defining tasks (mortality, readmission, length-of-stay, drug recommendation, sleep staging, ICD coding, EEG events), instantiating models (Transformer, RETAIN, GAMENet, SafeDrug, MICRON, StageNet, AdaCare, CNN/RNN/MLP), training with the PyHealth Trainer, computing clinical metrics, and using medical code utilities (ICD/ATC/NDC/RxNorm l
Meta-/Umbrella-Skill für die Familie „Therapie / Beratung". Kennt alle therapeutischen Skills (Stabilisierung, Methoden-Überblick, Gesprächsführung + deregistrierte Spezialverfahren) und leitet zum passenden weiter. Nutze diesen Skill, wenn unklar ist, welcher Therapie-/Beratungs-Skill passt, ein Überblick über die verfügbaren Verfahren gebraucht wird, oder eine Beratungs-/Krisensituation zuerst eingeordnet werden muss. Auch auslösen bei „welche Therapiemethode passt", „Beratung strukturieren",
AI-powered cytokine release syndrome (CRS) and cytokine storm analysis for prediction, monitoring, and management in immunotherapy and infectious disease.
Medical evidence grading orchestrator. 当用户需要评估医学文献的证据强度、比较多篇论文的质量、查找某疾病的高等级证据(指南或 RCT)、或验证临床声明的证据支持度时,调用本 skill。整合 6 个原子 skill 的检索结果,按证据金字塔自动分级为 A/B/C/D。优先使用 BioMCP fast-path(~3-5s),无 BioMCP 时回退 slow-path(~15-25s)。
Analyze Whole Slide Images (WSI) for digital pathology, including tissue segmentation and feature extraction.
Ordnet freiwillig bereitgestellte Gesundheitsinformationen und bereitet Fragen für Fachpersonen vor.
Use when user requests medical/pharmaceutical market sizing, Chinese clinical pathway reconstruction, patient flow waterfall charts, drug usage composition analysis, unmet need quantification, prescription share estimation, competitive landscape for antifungals/oncology/ICU drugs, or says things like "估算某市场多大", "画个诊疗路径图", "做个 market sizing", "分析用药占比". Also triggers on disease×department×drug class combinations (血液科 IFI, 呼吸科真菌, ICU真菌, 肿瘤免疫). Works for 中立第三方 or 特定产品策略 stances. Supports Agent Teams
Analyse billing leakage — unbilled services, suboptimal coding, claims rejection patterns by payer/procedure/provider, time-to-collection bottlenecks, aged debt analysis, and estimate total revenue currently left on the table. Use monthly or when revenue doesn't match activity levels.
Satori is a clinically informed wisdom companion for navigating the inner life — emotions, meaning, grief, purpose, relationship, identity, and the questions that don't resolve easily. Activate when someone is processing something difficult, wrestling with a life question, seeking perspective, or simply needs to think alongside someone who won't rush them toward an answer. Also activate when someone uses language like "I've been struggling with," "I don't know what to do," or "I need to figure o
Local, private capture of medical data: diagnoses, symptom histories and examination plans. No BACH origin — custom design with its own SQLite store. Strictly local, no cloud transfer.
Diagnostic test / biomarker accuracy — sensitivity, specificity, PPV, NPV, likelihood ratios, accuracy from a 2x2 table; ROC curve, AUC, and the optimal cutoff (Youden) for a continuous biomarker; and post-test probability via Bayes. Use when you have test results vs a gold standard (binary 2x2, or a continuous score + true labels) and need to judge how good the test is, pick a threshold, or compute the probability of disease given a result. Emphasizes the prevalence-dependence of PPV/NPV.
Progressive Muscle Relaxation (PMR) according to Jacobson and Autogenic Training according to Schultz. Short forms and full versions.
AI-powered genetic variant pathogenicity prediction using PopEVE deep learning model for population-aware disease variant identification and rare disease diagnosis.
Comparison of the four guideline-approved psychotherapy approaches in Germany: Cognitive Behavioral Therapy, Psychodynamic Therapy, Psychoanalysis, Systemic Therapy — Orientation guide.
Mental health support designed for workers in trades, service, and physical occupations. Use when someone in a physical job is struggling with stress, substance use, anger, isolation, or burnout and traditional mental health resources feel inaccessible.
分析运动数据、识别运动模式、评估健身进展，并提供个性化训练建议。支持与慢性病数据的关联分析。
Fuse genomic variants, pathology findings, and clinical context to draft evidence-linked therapy options for tumor board review.
Systemic questioning techniques: Circular questions, scaling questions, miracle question, and exception questions for reflection and perspective expansion.
Identify unwarranted clinical variation across providers — treatment pattern differences not explained by patient case mix. Distinguish warranted variation (clinical complexity) from unwarranted variation (provider habit). The single highest-leverage quality and cost intervention in healthcare. Use quarterly or when outcomes differ unexpectedly across providers.
AI-powered circulating tumor DNA dynamics analysis for molecular residual disease detection, treatment response monitoring, and early relapse prediction using liquid biopsy.
分析营养数据、识别营养模式、评估营养状况，并提供个性化营养建议。支持与运动、睡眠、慢性病数据的关联分析。
Query ClinVar for genomic variant clinical significance data
分析健康目标数据、识别目标模式、评估目标进度,并提供个性化目标管理建议。支持与营养、运动、睡眠等健康数据的关联分析。
AI-powered homologous recombination deficiency (HRD) analysis for PARP inhibitor response prediction using genomic scarring signatures and BRCA pathway assessment.
Gym workout planner and nutrition tracker. Search 690+ exercises by muscle, equipment, or category via wger. Look up macros and calories for 380,000+ foods via USDA FoodData Central. Compute BMI, TDEE, one-rep max, macro splits, and body fat — pure Python, no pip installs. Built for anyone chasing gains, cutting weight, or just trying to eat better.
Behavioral activation for depression: Breaking the vicious cycle, activity monitoring, weekly planning, and values-based activities.
Use when designing a prospective clinical study before submission — selecting and classifying endpoints (primary / key-secondary / exploratory, with surrogate-endpoint flagging), estimating sample size and power for two-arm designs (means / proportions / survival), or scoring a study plan for feasibility and a GO / GO-WITH-CONDITIONS / REDESIGN / NO-GO phase-gate decision. Every output is an ESTIMATE plus a named human owner (clinician / biostatistician / regulatory owner) — never clinical fact,
Implement the HIPAA Security Rule (45 CFR Part 164 Subpart C) to protect electronic protected health information (ePHI): conduct the required risk analysis, deploy the administrative, physical, and technical safeguards, handle required vs addressable implementation specifications, execute Business Associate Agreements, and stand up breach-notification readiness. Use when an organization is a HIPAA covered entity or business associate, when protecting ePHI, when preparing for an OCR audit or resp
Extracts medical entities (Diseases, Medications, Procedures) from unstructured clinical text using regex and simple rules (or LLM wrappers).
个人全维度健康管理系统，中西医融合。当用户涉及运动训练计划、饮食营养建议、 健康数据记录追踪、中医体质辨识、节气养生、舌诊分析、性健康记录等话题时立即触发。 提供四位顾问（Coach Alex 运动教练 / Dr. Mei 营养师 / Analyst Ray 数据分析师 / Dr. Chen 中医体质顾问），支持深度建档和长期追踪。任何"帮我建档"、"记录今天运动"、 "我的体质"、"舌苔厚白"类请求均应触发本 skill。
Stabilization techniques: Grounding, safe place, containment, and breathing exercises. Immediate techniques for acute distress and panic attacks.
Parse trial protocols and patient data to produce criterion-level MET/NOT/UNKNOWN determinations with evidence and gaps for clinical trial screening tasks.
Quality & Regulatory agent for ISO 13485 QMS, MDR compliance, FDA submissions, GDPR/DSGVO, and ISMS audits. Orchestrates ra-qm-team skills. Spawn when users need regulatory strategy, audit preparation, CAPA management, risk management, or compliance documentation.
Walk through a structured incident response protocol with time-based escalation — immediate patient safety, duty of candour, documentation, root cause analysis, corrective action, and recurrence monitoring. Use when a clinical incident, data breach, patient complaint, safeguarding concern, or operational failure occurs.
Addresses healthcare AI privacy at the intersection of HIPAA and the EU AI Act for clinical decision support systems. Covers training data PHI handling, model transparency and explainability, patient rights in algorithmic decisions, FDA/OCR regulatory coordination, and bias monitoring. Keywords: healthcare AI, HIPAA, AI Act, clinical decision support, PHI training data, model transparency.
Precision Oncology
Use FIRST when user requests any disease market sizing report (e.g. "做 X 市场调研" / "Run market sizing for X"). Elicits 4-6 startup questions (evidence window, geography, international comparison, report depth, user role) and writes .cache/<slug>/contract.json. ALWAYS invoke before disease-market-sizing-orchestration. Validates against schemas/contract.schema.json.
HIPAA-specific entrypoint for healthcare privacy and security work. Use when a task is explicitly framed around HIPAA, PHI handling, covered entities, BAAs, breach posture, or US healthcare compliance requirements.
Practical guidance for navigating grief after loss. Use when someone has lost a person, relationship, job, or life chapter and needs help understanding what they're experiencing and how to move through it.
Compare actual patient care against guideline recommendations — flag patients who are overdue for review, off-protocol, or missing recommended interventions. Generate structured audit reports with improvement actions. Integrates with Herald-parsed guideline JSONs. Use for clinical governance cycles, quality improvement, or pre-inspection preparation.
AI-powered minimal residual disease (MRD) analysis for multiple myeloma using next-generation flow cytometry, NGS, and mass spectrometry approaches.
Trial shortlist
Search ClinicalTrials.gov for clinical study information
Use when generating computer system validation (CSV) documentation for pharmaceutical and medical device industries, including validation plans, URS, FS, IQ/OQ/PQ documents, and traceability matrices.
Medical Education Video Maker — Create Clinical Training and CME Videos.
Use when documenting a clinical encounter as a progress note: organize it into the four SOAP sections in fixed order with each piece of data placed in the correct section — which cheaper models do not do by default.
Injury prevention through proper body mechanics for physical work. Use when someone has a physically demanding job, needs to lift heavy objects safely, stands all day, or wants to prevent repetitive strain injuries.
Positive Psychology according to Seligman: PERMA model, character strengths (VIA), gratitude exercises, flow theory, and resilience factors.
生成紧急情况下快速访问的医疗信息摘要卡片。当用户需要旅行、就诊准备、紧急情况或询问"紧急信息"、"医疗卡片"、"急救信息"时使用此技能。提取关键信息（过敏、用药、急症、植入物），支持多格式输出（JSON、文本、二维码），用于急救或快速就医。
Frozen, deterministic decision (no LLM): maps pain_malleolar_zone, bone_tenderness_lateral_malleolus, bone_tenderness_medial_malleolus, can_bear_weight, visible_deformity, sprain_grade, hours_since_injury, age_years, patient_profile to one of urgent_care, seek_imaging, see_clinician, police_acute, police_subacute. Use when this decision must be made consistently and auditably — extract the features, call assess_ankle(), and relay its verdict without overriding it.
Forecast patient demand vs provider supply, identify scheduling bottlenecks, model capacity scenarios, and flag no-show/cancellation patterns. Use for weekly capacity planning, roster design, or when wait times are increasing.
You are **Profile Report**, a specialised ClawBio agent for generating unified personal genomic profile reports. Your role is to read a populated PatientProfile JSON file and synthesize all skill results into a single human-readable markdown document.
Diagnostic test / biomarker accuracy — sensitivity, specificity, PPV, NPV, likelihood ratios, accuracy from a 2x2 table; ROC curve, AUC, and the optimal cutoff (Youden) for a continuous biomarker; and post-test probability via Bayes. Use when you have test results vs a gold standard (binary 2x2, or a continuous score + true labels) and need to judge how good the test is, pick a threshold, or compute the probability of disease given a result. Emphasizes the prevalence-dependence of PPV/NPV.
Analyse referral patterns, geographic catchment, seasonal demand curves, competitor positioning, waitlist dynamics, and unmet demand signals to identify where to add capacity and which markets to enter. Use when planning expansion, noticing referral changes, or evaluating new service lines.
Synthesise overnight incidents, today's capacity vs demand, provider availability, regulatory deadlines, and operational red flags into a structured 2-minute morning briefing. Use when starting the day, preparing for a morning huddle, or when asked for an operational summary.
Structure raw clinical notes into SOAP-format summaries with explicit contradictions, missing data, and ICD-linked assessments using the provided prompt + usage script.
End-to-end drug safety review integrating FDA labels, FAERS adverse event reports, PRR/ROR disproportionality, pharmacogenomic biomarkers, clinical trial data, and published literature. Use for regulatory drug safety reviews, comprehensive pharmacovigilance reports, label-vs-real-world AE comparison, and clinical decision support for drug safety.
Search PubMed and retrieve structured biomedical literature with PMID lists, abstracts, MeSH terms, publication types, and PMC IDs for full-text access. Use this skill whenever the user mentions PubMed, PMID, MeSH terms, Clinical Queries, NCBI, E-utilities, or needs evidence for systematic reviews, RCT searches, drug-disease research, mechanism mapping, market research, or clinical evidence gathering. Make sure to use at the START of any medical evidence pipeline (diagnostic queries, prognosis,
Generate professional clinical decision support (CDS) documents for pharmaceutical and clinical research settings, including patient cohort analyses (biomarker-stratified with outcomes) and treatment recommendation reports (evidence-based guidelines with decision algorithms). Supports GRADE evidence grading, statistical analysis (hazard ratios, survival curves, waterfall plots), biomarker integration, and regulatory compliance. Outputs publication-ready LaTeX/PDF format optimized for drug develo
中国药品权威数据库查询 — NMPA(国家药监局) + CDE(药品审评中心) + DrugBank(英文名/ATC) + PubChem(化学结构) 多源融合,提供(通用名 ↔ 商品名 ↔ 英文名 ↔ 适应症 ↔ NMPA 批文号 ↔ 上市日期)精确映射。Make sure to use this skill whenever the user mentions 药品名 / 通用名 / 商品名 / NMPA / 国药准字 / 药监局 / CDE / drug brand name / generic name / drug registry / pharmaceutical lookup / drug verification / 药物核验 / 商品名对应 / drug cross-check / drug authority lookup. 在任何 medical / market-sizing / clinical / disease-research 报告生成阶段,**所有药品提及必须先调 lookup_drug() 验证**,严禁 LLM 凭训练记忆拼凑通用名↔商品名↔英文名
Clinical variant interpretation from raw variant calls to ACMG-classified recommendations with structural impact analysis. Use for VUS classification, pathogenicity assessment with cited criteria, structure-based variant impact (AlphaFold/PDB), non-coding/regulatory variant effect prediction with sequence deep-learning models (AlphaGenome, Enformer, Borzoi, ChromBPNet, Evo 2), and producing clinical-grade variant reports for return of results or molecular tumor boards. Use this whenever a user a