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Strategy: Research design-level FMEA — function analysis, failure mode identification, severity/occurrence/detection scoring per AIAG-VDA 2019.
Passed 9 of 22 test cases with the skill, and 13 of 22 without it.
2 fixed17 passed either way1 still failing2 broke
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One of 2 test cases the skill fixed. Same model, same prompt, with and without the skill.
I'm setting up an automated high-throughput RNA sequencing pipeline for our genomics lab. I need a systematic Design FMEA to evaluate potential points of failure in the experimental setup. Please break down the pipeline into functional components, identify how each function can fail along with root causes and downstream impacts, score the risks based on severity, likelihood, and detectability, rank their action priorities, and outline specific mitigation plans for the top risks.
| Checked | Without skill | With skill |
|---|---|---|
| The analysis presents a hierarchical function tree decomposition of the RNA sequencing pipeline prior to listing failure modes. | Missed | Passed |
| The output assigns action priority levels to failure modes. | Passed | Passed |
The instructions your model reads when the skill loads.
Systematic failure analysis at the research design level: what functions can fail, how, and with what consequence?
| Parameter | S | M | L |
|---|---|---|---|
| Functions analyzed | 4 | 10 | 20 |
| Failure modes per function | 2 | 3 | 5 |
| Chain depth (cause levels) | 2 | 4 | 6 |
| Mitigations designed | 3 | 8 | 15 |
function-analysis → failure-mode-extraction → failure-chain-construction
→ [severity-scoring, occurrence-scoring, detection-scoring] (parallel)
→ action-priority-matrix → mitigation-design-sop
→ re-scoring (mitigation-validation tactic)
test cases passed, vs 13 / 22 without
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