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💞 GenomeMatch · clawbio | DecimalAI

scienceby clawbio

💞 GenomeMatch

clawbio/genome-match

Source clawbio/clawbio ↗License MIT

Score genetic compatibility across all male-female pairings in a Genomebook generation

SkillScore91Maintained

Automatic

Research pack

Last verified 8/16/2026

What it changes

Passed 18 of 20 test cases with the skill, and 7 of 20 without it.

Without skill36%

With skill91%

Checks it passed that the model alone missed

States that the composite score ranges from 0.0 to 1.0
Identifies generation 0 as the default target generation
States that the disease risk penalty carries a 20% weight

and 10 more in the full report

12 fixed8 passed either way2 still failing0 broke

Pass-rate lift: +55 pp
Tokens: -22%
Agent turns: 0%
Response time: -59%

Model gemini-3.6-flashMeasured 8/16/2026v120 of 22 cases passed with skill · 20 comparable

Tokens, turns and time describe resource use, not a dollar price.

Use this skill

Save it into your project's skills folder. Claude Code picks it up in its next session.

curl -fsSL --create-dirs -o .claude/skills/clawbio-genome-match/SKILL.md https://app.decimal.ai/s/clawbio-genome-match/SKILL.md

Want it pinned and updatable? pip install "decimalai>=0.15", then decimalai skills add clawbio-genome-match, and start Claude Code with claude --plugin-dir "$(git rev-parse --show-toplevel)/.agents"

1 · One-time — install the CLI (docs ↗)

pip install "decimalai>=0.15"

2 · Get the skill — writes .agents/skills/clawbio-genome-match/ and pins it in .decimal/skills.lock

decimalai skills add clawbio-genome-match

No CLI? Get the same file — curl · raw file

curl -fsSL --create-dirs -o .claude/skills/clawbio-genome-match/SKILL.md https://app.decimal.ai/s/clawbio-genome-match/SKILL.md

Raw file: /s/clawbio-genome-match/SKILL.md ↗ · machine-readable summary at /s/clawbio-genome-match.json ↗

Safety checks: 3 of 3 passed

Code scan CleanIntent PassedContent Clean

See it in action

One of 11 test cases the skill fixed. Same model, same prompt, with and without the skill.

1 of 11

Prompt

If someone executes python skills/genome-match/genome_match.py without specifying any CLI parameters, which generation's genome dataset is analyzed by default?

What was checked, without and with the skill
Checked	Without skill	With skill
Identifies generation 0 as the default target generation	Missed	Passed

case-21 · gemini-3.6-flash · 8/16/2026 · answers are capped and redacted

What's inside

The instructions your model reads when the skill loads.

SKILL.md60 linessingle file

💞 GenomeMatch

Purpose

Score genetic compatibility between all male-female pairings in a Genomebook generation. The engine evaluates heterozygosity advantage, disease carrier risk, and trait complementarity to rank optimal mating pairs for the next generation.

How It Works

Load genomes for a target generation from GENOMEBOOK/DATA/GENOMES/.
Compute pairwise compatibility for every M x F combination:
- Heterozygosity score (40%): fraction of loci where offspring would be heterozygous (genetic diversity advantage).
- Trait complementarity (40%): reward balanced trait combinations and high average trait values across the pair.
- Disease risk penalty (20%): flag pairs where both parents carry recessive disease alleles (25% affected offspring risk per flagged condition).
Rank all pairings by composite score (0.0 to 1.0).
Select non-overlapping mating pairs via greedy selection from the top of the ranked list (each individual mates at most once per generation).

Input

GENOMEBOOK/DATA/GENOMES/*.genome.json
GENOMEBOOK/DATA/disease_registry.json

Output

Ranked compatibility table (all M x F pairings)
Selected mating pairs for the next generation

CLI Usage

# Score all pairings for generation 0
python skills/genome-match/genome_match.py

# Score a specific generation
python skills/genome-match/genome_match.py --generation 1

Track record

Benchmark

18 / 20

test cases passed, vs 7 / 20 without

Adoption

Users: 0
Times used: 0

Safety and source details

SkillSafety

✓ 3 of 3 passed

Code scan15 of 15 checks clean

0 critical · 0 warning · 0 info — scanner v4 — 8/3/2026

View 15 scanner checks

live_secretremote_code_executionreverse_shelldata_exfiltrationssrf_metadataagent_snoopinganti_refusaldestructive_commandsobfuscated_unicodeunicode_homoglyphopaque_blobsuspicious_urltool_overreachtrigger_abuseprompt_injection_phrasing

IntentSafe

LLM judge · does the skill do what it claims

ContentClean

LLM judge · policy & harmful-content review

Source

Imported

clawbio / clawbio

skills/genome-match/SKILL.md

View on GitHub ↗

License MITImported 8/3/2026Version v1

More skills from the same source and nearby in the registry, with their headline benchmark lift.

Ready to supercharge your AI agents?

See it in action

What's inside

💞 GenomeMatch

Purpose

How It Works

Input

Output

CLI Usage

Track record

Benchmark

Adoption

SkillSafety

Source

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